Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain

Abstract Movement-evoked pain in chronic low back pain (LBP) can be influenced by visual cues linked to threatening movements. This study explored whether manipulating visual proprioceptive feedback via virtual reality (VR) alters movement-evoked pain and if individuals with higher pain, kinesiophob...

Full description

Saved in:
Bibliographic Details
Main Authors: Jaime Jordán-López, María D. Arguisuelas, Julio Doménech, M. Lourdes Peñalver-Barrios, Marta Miragall, Rocío Herrero, Rosa M. Baños, Juan J. Amer-Cuenca, Juan F. Lisón
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-08094-z
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849238605396967424
author Jaime Jordán-López
María D. Arguisuelas
Julio Doménech
M. Lourdes Peñalver-Barrios
Marta Miragall
Rocío Herrero
Rosa M. Baños
Juan J. Amer-Cuenca
Juan F. Lisón
author_facet Jaime Jordán-López
María D. Arguisuelas
Julio Doménech
M. Lourdes Peñalver-Barrios
Marta Miragall
Rocío Herrero
Rosa M. Baños
Juan J. Amer-Cuenca
Juan F. Lisón
author_sort Jaime Jordán-López
collection DOAJ
description Abstract Movement-evoked pain in chronic low back pain (LBP) can be influenced by visual cues linked to threatening movements. This study explored whether manipulating visual proprioceptive feedback via virtual reality (VR) alters movement-evoked pain and if individuals with higher pain, kinesiophobia, disability, or catastrophising are more susceptible to these manipulations. Cross-sectional study with 50 patients with non-specific chronic LBP. Participants performed lumbar spine extension until pain onset with and without VR. VR feedback was manipulated to show 10% less (E −) or 10% more (E +) movement than actual extension. Range of motion (ROM) was measured using an electro-goniometer. Within-group differences across control (E), E −, and E + conditions were assessed with Friedman tests. VR underestimation (E −) led to a 20% increase in ROM compared to the control (E; p = 0.002) and a 22% increase compared to overestimation (E +; p < 0.001). Patients with higher kinesiophobia and disability showed greater improvement in the E − condition. Manipulating visual-proprioceptive information through VR altered pain thresholds in chronic LBP. Underestimated movement (E −) delayed pain onset by extending ROM. Kinesiophobia and disability significantly influenced susceptibility to visual feedback.
format Article
id doaj-art-3ba2ff1fa27c4f72aa46cca3fea0d2c0
institution Kabale University
issn 2045-2322
language English
publishDate 2025-07-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj-art-3ba2ff1fa27c4f72aa46cca3fea0d2c02025-08-20T04:01:34ZengNature PortfolioScientific Reports2045-23222025-07-011511910.1038/s41598-025-08094-zVisual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back painJaime Jordán-López0María D. Arguisuelas1Julio Doménech2M. Lourdes Peñalver-Barrios3Marta Miragall4Rocío Herrero5Rosa M. Baños6Juan J. Amer-Cuenca7Juan F. Lisón8Department of Biomedical Sciences, School of Health Sciences, Universidad Cardenal Herrera-CEU, CEU UniversitiesDepartment of Physiotherapy, School of Health Sciences, Universidad Cardenal Herrera-CEU, CEU UniversitiesDepartment of Orthopaedic Surgery and Traumatology, Clínica Universidad de NavarraDepartment of Physical Medicine and Rehabilitation, Hospital Arnau de VilanovaCIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos IIICIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos IIICIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos IIIDepartment of Physiotherapy, School of Health Sciences, Universidad Cardenal Herrera-CEU, CEU UniversitiesDepartment of Biomedical Sciences, School of Health Sciences, Universidad Cardenal Herrera-CEU, CEU UniversitiesAbstract Movement-evoked pain in chronic low back pain (LBP) can be influenced by visual cues linked to threatening movements. This study explored whether manipulating visual proprioceptive feedback via virtual reality (VR) alters movement-evoked pain and if individuals with higher pain, kinesiophobia, disability, or catastrophising are more susceptible to these manipulations. Cross-sectional study with 50 patients with non-specific chronic LBP. Participants performed lumbar spine extension until pain onset with and without VR. VR feedback was manipulated to show 10% less (E −) or 10% more (E +) movement than actual extension. Range of motion (ROM) was measured using an electro-goniometer. Within-group differences across control (E), E −, and E + conditions were assessed with Friedman tests. VR underestimation (E −) led to a 20% increase in ROM compared to the control (E; p = 0.002) and a 22% increase compared to overestimation (E +; p < 0.001). Patients with higher kinesiophobia and disability showed greater improvement in the E − condition. Manipulating visual-proprioceptive information through VR altered pain thresholds in chronic LBP. Underestimated movement (E −) delayed pain onset by extending ROM. Kinesiophobia and disability significantly influenced susceptibility to visual feedback.https://doi.org/10.1038/s41598-025-08094-zChronic low back painVirtual realityMovement evoked-painIllusionsVisual-proprioceptive cuesModulation
spellingShingle Jaime Jordán-López
María D. Arguisuelas
Julio Doménech
M. Lourdes Peñalver-Barrios
Marta Miragall
Rocío Herrero
Rosa M. Baños
Juan J. Amer-Cuenca
Juan F. Lisón
Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain
Scientific Reports
Chronic low back pain
Virtual reality
Movement evoked-pain
Illusions
Visual-proprioceptive cues
Modulation
title Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain
title_full Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain
title_fullStr Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain
title_full_unstemmed Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain
title_short Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain
title_sort visual feedback manipulation in virtual reality alters movement evoked pain perception in chronic low back pain
topic Chronic low back pain
Virtual reality
Movement evoked-pain
Illusions
Visual-proprioceptive cues
Modulation
url https://doi.org/10.1038/s41598-025-08094-z
work_keys_str_mv AT jaimejordanlopez visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT mariadarguisuelas visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT juliodomenech visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT mlourdespenalverbarrios visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT martamiragall visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT rocioherrero visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT rosambanos visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT juanjamercuenca visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain
AT juanflison visualfeedbackmanipulationinvirtualrealityaltersmovementevokedpainperceptioninchroniclowbackpain