Yellow fever disease severity and endothelial dysfunction are associated with elevated serum levels of viral NS1 protein and syndecan-1Research in context

Yellow fever disease severity and endothelial dysfunction are associated with elevated serum levels of viral NS1 protein and syndecan-1Research in context

Summary: Background: Yellow fever virus (YFV) infections are a major global disease concern with high mortality in humans, and as such it is critical to identify clinical correlates of disease severity. While nonstructural protein 1 (NS1) of the related dengue virus is implicated in contributing to...

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Main Authors: Francielle T.G. de Sousa, Colin M. Warnes, Erika R. Manuli, Laurentia V. Tjang, Pedro H. Carneiro, Luzia Maria de Oliveira Pinto, Arash Ng, Samhita Bhat, Jose Victor Zambrana, Luiz G.F.A.B. D’Elia Zanella, Yeh-Li Ho, Camila M. Romano, P. Robert Beatty, Scott B. Biering, Esper G. Kallas, Ester C. Sabino, Eva Harris
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:EBioMedicine
Subjects:
Yellow fever
Pathogenesis
Endothelial dysfunction
NS1
Syndecan-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004456
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