γ-Glutamyl transpeptidase-activable nanoprobe crosses the blood-brain barrier for immuno-sonodynamic therapy of glioma

γ-Glutamyl transpeptidase-activable nanoprobe crosses the blood-brain barrier for immuno-sonodynamic therapy of glioma

Abstract Effective treatment against glioma remains challenging nowadays because the protective blood-brain barrier (BBB) impedes drug penetration into brain and the limited efficacy of conventional chemotherapy. While strong positively charged nanoparticles have good permeability through the BBB, t...

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Bibliographic Details
Main Authors:	Bo Li, Gengjia Chen, Huihai Zhong, Tan Li, Minzhao Lin, Huiye Wei, Qiaoyun Zhang, Qi Chen, Jinsheng Huang, Xintao Shuai
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-024-54382-z
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