Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs

The metabolic syndrome, made up of the sum of the entities that define it (obesity, hypertension, dyslipidemias and non-alcoholic hepatic steatosis) has gained an important place in the research of the last decades. This aspect is mainly due to the complexity of management in pediatric practice. The...

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Main Authors: Otilia Elena Frăsinariu, Vasile Valeriu Lupu, Laura Mihaela Trandafir, Violeta Streanga, Elena Jechel, Iris Bararu-Bojan, Ioana Vasiliu, Magdalena Cuciureanu, Isabela Ioana Loghin, Costica Mitrofan, Alin Horatiu Nedelcu, Anton Knieling, Ancuta Lupu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2024.1475111/full
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author Otilia Elena Frăsinariu
Vasile Valeriu Lupu
Laura Mihaela Trandafir
Violeta Streanga
Elena Jechel
Iris Bararu-Bojan
Ioana Vasiliu
Magdalena Cuciureanu
Isabela Ioana Loghin
Costica Mitrofan
Alin Horatiu Nedelcu
Anton Knieling
Ancuta Lupu
author_facet Otilia Elena Frăsinariu
Vasile Valeriu Lupu
Laura Mihaela Trandafir
Violeta Streanga
Elena Jechel
Iris Bararu-Bojan
Ioana Vasiliu
Magdalena Cuciureanu
Isabela Ioana Loghin
Costica Mitrofan
Alin Horatiu Nedelcu
Anton Knieling
Ancuta Lupu
author_sort Otilia Elena Frăsinariu
collection DOAJ
description The metabolic syndrome, made up of the sum of the entities that define it (obesity, hypertension, dyslipidemias and non-alcoholic hepatic steatosis) has gained an important place in the research of the last decades. This aspect is mainly due to the complexity of management in pediatric practice. The main directions in his approach therefore bring together the concern of counteracting the noise or systemic, of the multiple intercurrents at the physiopathological level, as well as the negative imprint exerted on the quality of life. Its appearance and evolution are currently controversial topics, but the influence of genetic predisposition and lifestyle (diet, physical activity, psychological balance) are certainties. Considering the escalation of the incident at the global level, it is self-evident that it is necessary to know the pathogenesis and practice countermeasures for prophylactic or therapeutic purposes. The present work aims to summarize general aspects related to the metabolic syndrome encountered in pediatric age, with an emphasis on complementary therapeutic perspectives and their effectiveness, by analyzing the latest data from the specialized literature, accessed with the help of international databases (e.g., PubMed, Web of Science, Scopus, Embase, Google Scholar).
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publisher Frontiers Media S.A.
record_format Article
series Frontiers in Nutrition
spelling doaj-art-3b7a06846ef2474480c04e5569cb19f42024-12-11T14:57:00ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2024-12-011110.3389/fnut.2024.14751111475111Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugsOtilia Elena Frăsinariu0Vasile Valeriu Lupu1Laura Mihaela Trandafir2Violeta Streanga3Elena Jechel4Iris Bararu-Bojan5Ioana Vasiliu6Magdalena Cuciureanu7Isabela Ioana Loghin8Costica Mitrofan9Alin Horatiu Nedelcu10Anton Knieling11Ancuta Lupu12Faculty of Medicine, Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaFaculty of Medicine, Pediatrics, “Grigore T. Popa” University of Medicine and Pharmacy, Iași, RomaniaThe metabolic syndrome, made up of the sum of the entities that define it (obesity, hypertension, dyslipidemias and non-alcoholic hepatic steatosis) has gained an important place in the research of the last decades. This aspect is mainly due to the complexity of management in pediatric practice. The main directions in his approach therefore bring together the concern of counteracting the noise or systemic, of the multiple intercurrents at the physiopathological level, as well as the negative imprint exerted on the quality of life. Its appearance and evolution are currently controversial topics, but the influence of genetic predisposition and lifestyle (diet, physical activity, psychological balance) are certainties. Considering the escalation of the incident at the global level, it is self-evident that it is necessary to know the pathogenesis and practice countermeasures for prophylactic or therapeutic purposes. The present work aims to summarize general aspects related to the metabolic syndrome encountered in pediatric age, with an emphasis on complementary therapeutic perspectives and their effectiveness, by analyzing the latest data from the specialized literature, accessed with the help of international databases (e.g., PubMed, Web of Science, Scopus, Embase, Google Scholar).https://www.frontiersin.org/articles/10.3389/fnut.2024.1475111/fullmetabolic syndromechildpathophysiologycomplementary therapieslifestyle modificationMediterranean diet
spellingShingle Otilia Elena Frăsinariu
Vasile Valeriu Lupu
Laura Mihaela Trandafir
Violeta Streanga
Elena Jechel
Iris Bararu-Bojan
Ioana Vasiliu
Magdalena Cuciureanu
Isabela Ioana Loghin
Costica Mitrofan
Alin Horatiu Nedelcu
Anton Knieling
Ancuta Lupu
Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs
Frontiers in Nutrition
metabolic syndrome
child
pathophysiology
complementary therapies
lifestyle modification
Mediterranean diet
title Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs
title_full Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs
title_fullStr Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs
title_full_unstemmed Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs
title_short Metabolic syndrome therapy in pediatric age — between classic and modern. From diets to pipeline drugs
title_sort metabolic syndrome therapy in pediatric age between classic and modern from diets to pipeline drugs
topic metabolic syndrome
child
pathophysiology
complementary therapies
lifestyle modification
Mediterranean diet
url https://www.frontiersin.org/articles/10.3389/fnut.2024.1475111/full
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