Photo-Induced Aerobic Oxidation of C–H Bonds
The photo-induced aerobic oxidation of C–H bonds has become an increasingly valuable strategy in organic synthesis, offering a green and efficient method for introducing oxygen into organic molecules. The utilization of molecular oxygen as an oxidant, coupled with visible-light photocatalysis, has g...
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MDPI AG
2024-11-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/29/22/5277 |
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| _version_ | 1846152839560167424 |
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| author | Haolin Chen Feng Liu |
| author_facet | Haolin Chen Feng Liu |
| author_sort | Haolin Chen |
| collection | DOAJ |
| description | The photo-induced aerobic oxidation of C–H bonds has become an increasingly valuable strategy in organic synthesis, offering a green and efficient method for introducing oxygen into organic molecules. The utilization of molecular oxygen as an oxidant, coupled with visible-light photocatalysis, has gained significant attention due to its sustainability, atom economy, and environmentally benign nature. This review highlights the recent advancements in the field, focusing on the development of metal-free and transition-metal-based photocatalytic systems and novel photosensitizers capable of promoting selective C–H bond oxidation. The mechanistic pathways involved in various substrate oxidations, including benzylic, alkyl, alkene, and alkyne C–H bond transformations, are discussed. This review concludes with insights into the potential for integrating photocatalysis with renewable energy sources, positioning photo-induced aerobic oxidation as a cornerstone of sustainable chemical processes. |
| format | Article |
| id | doaj-art-3b792071cf184b5ea2cf4e3aeedce477 |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-3b792071cf184b5ea2cf4e3aeedce4772024-11-26T18:15:24ZengMDPI AGMolecules1420-30492024-11-012922527710.3390/molecules29225277Photo-Induced Aerobic Oxidation of C–H BondsHaolin Chen0Feng Liu1Department of Chemistry, Fudan University, Shanghai 200438, ChinaDepartment of Chemistry, Fudan University, Shanghai 200438, ChinaThe photo-induced aerobic oxidation of C–H bonds has become an increasingly valuable strategy in organic synthesis, offering a green and efficient method for introducing oxygen into organic molecules. The utilization of molecular oxygen as an oxidant, coupled with visible-light photocatalysis, has gained significant attention due to its sustainability, atom economy, and environmentally benign nature. This review highlights the recent advancements in the field, focusing on the development of metal-free and transition-metal-based photocatalytic systems and novel photosensitizers capable of promoting selective C–H bond oxidation. The mechanistic pathways involved in various substrate oxidations, including benzylic, alkyl, alkene, and alkyne C–H bond transformations, are discussed. This review concludes with insights into the potential for integrating photocatalysis with renewable energy sources, positioning photo-induced aerobic oxidation as a cornerstone of sustainable chemical processes.https://www.mdpi.com/1420-3049/29/22/5277photocatalysisaerobic oxidationC–H bond activationvisible lightgreen chemistry |
| spellingShingle | Haolin Chen Feng Liu Photo-Induced Aerobic Oxidation of C–H Bonds Molecules photocatalysis aerobic oxidation C–H bond activation visible light green chemistry |
| title | Photo-Induced Aerobic Oxidation of C–H Bonds |
| title_full | Photo-Induced Aerobic Oxidation of C–H Bonds |
| title_fullStr | Photo-Induced Aerobic Oxidation of C–H Bonds |
| title_full_unstemmed | Photo-Induced Aerobic Oxidation of C–H Bonds |
| title_short | Photo-Induced Aerobic Oxidation of C–H Bonds |
| title_sort | photo induced aerobic oxidation of c h bonds |
| topic | photocatalysis aerobic oxidation C–H bond activation visible light green chemistry |
| url | https://www.mdpi.com/1420-3049/29/22/5277 |
| work_keys_str_mv | AT haolinchen photoinducedaerobicoxidationofchbonds AT fengliu photoinducedaerobicoxidationofchbonds |