Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis
With a logistical advantage, new wire-free procedures have simplified implantation and retrieval of non-palpable breast cancers with enhanced clinical outcomes. The objective of current systematic review and meta-analysis is to assess the clinical effectiveness between three new wireless non-radiati...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-09-01
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| Series: | Clinical Surgical Oncology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773160X24000199 |
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| author | Kumaresh Timma Subramanian Abdolazeem Elnour Vijay Kurup |
| author_facet | Kumaresh Timma Subramanian Abdolazeem Elnour Vijay Kurup |
| author_sort | Kumaresh Timma Subramanian |
| collection | DOAJ |
| description | With a logistical advantage, new wire-free procedures have simplified implantation and retrieval of non-palpable breast cancers with enhanced clinical outcomes. The objective of current systematic review and meta-analysis is to assess the clinical effectiveness between three new wireless non-radiation localisation techniques, such as Magseed, Radiofrequency identification TAG and Savi-scout reflector from published literature over a 3 year period. The study, following PRISMA guidelines, identified 26 studies from 2020 to 2022 involving 6275 innovative agents, analyzing three groups. Statistical analysis using Medcalc software showed a pooled positive margin rate of 12.28% (95% CI, 10–15%) and a re-excision rate of 11.29% (95%CI, 9–14%) for all three wireless group combined whereas studies that compare them with wire showed higher positive margin rate of 14.87% (95% CI, 12–18%) and re-excision rate of 16.23% (95% CI, 14–18%) for wire-guided localisation. Compared with odd's ratio, there was no statistical significance for margin involvement between WGL and novel agents OR 0.870 95% CI (0.707–1.071); z=-1.310 p=0.190; however, there was a statistical significance with fewer re-excision for wireless group OR 0.791; 95% CI (0.648–0.965); z=-2.309 p=0.021. In sub group analysis with kruskal-wallis test, there was no statistical significance between each group for both margin-positivity (p=0.797; Chi2 0.605) and re-excision rates (p=0.464; chi21.535). Consolidated insertion and retrieval success for wireless group were 98.13% and 99.13% respectively whereas WGL had a similar retrieval success rate of 99.63%. To establish the best localisation approach, future prospective randomised trials will be required to assess quantitative cost-effective analyses. |
| format | Article |
| id | doaj-art-3b6aafd7237d48639cfa766303a85bc4 |
| institution | Kabale University |
| issn | 2773-160X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Surgical Oncology |
| spelling | doaj-art-3b6aafd7237d48639cfa766303a85bc42024-11-23T06:35:03ZengElsevierClinical Surgical Oncology2773-160X2024-09-0133100051Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysisKumaresh Timma Subramanian0Abdolazeem Elnour1Vijay Kurup2Lancashire Teaching Hospitals NHS Foundation Trust, United Kingdom; Corresponding author.Hywel Dda University Health Board, United KingdomNorth Tees and Hartlepool NHS Trust, United KingdomWith a logistical advantage, new wire-free procedures have simplified implantation and retrieval of non-palpable breast cancers with enhanced clinical outcomes. The objective of current systematic review and meta-analysis is to assess the clinical effectiveness between three new wireless non-radiation localisation techniques, such as Magseed, Radiofrequency identification TAG and Savi-scout reflector from published literature over a 3 year period. The study, following PRISMA guidelines, identified 26 studies from 2020 to 2022 involving 6275 innovative agents, analyzing three groups. Statistical analysis using Medcalc software showed a pooled positive margin rate of 12.28% (95% CI, 10–15%) and a re-excision rate of 11.29% (95%CI, 9–14%) for all three wireless group combined whereas studies that compare them with wire showed higher positive margin rate of 14.87% (95% CI, 12–18%) and re-excision rate of 16.23% (95% CI, 14–18%) for wire-guided localisation. Compared with odd's ratio, there was no statistical significance for margin involvement between WGL and novel agents OR 0.870 95% CI (0.707–1.071); z=-1.310 p=0.190; however, there was a statistical significance with fewer re-excision for wireless group OR 0.791; 95% CI (0.648–0.965); z=-2.309 p=0.021. In sub group analysis with kruskal-wallis test, there was no statistical significance between each group for both margin-positivity (p=0.797; Chi2 0.605) and re-excision rates (p=0.464; chi21.535). Consolidated insertion and retrieval success for wireless group were 98.13% and 99.13% respectively whereas WGL had a similar retrieval success rate of 99.63%. To establish the best localisation approach, future prospective randomised trials will be required to assess quantitative cost-effective analyses.http://www.sciencedirect.com/science/article/pii/S2773160X24000199Non-palpable breast cancerLocalisationMagseedRadio frequency tag (RFID)Savi-scout reflectorWire |
| spellingShingle | Kumaresh Timma Subramanian Abdolazeem Elnour Vijay Kurup Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis Clinical Surgical Oncology Non-palpable breast cancer Localisation Magseed Radio frequency tag (RFID) Savi-scout reflector Wire |
| title | Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis |
| title_full | Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis |
| title_fullStr | Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis |
| title_full_unstemmed | Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis |
| title_short | Comparison of three new wireless non-radiation techniques for localisation of non-palpable breast cancer - An updated systematic review and pooled meta-analysis |
| title_sort | comparison of three new wireless non radiation techniques for localisation of non palpable breast cancer an updated systematic review and pooled meta analysis |
| topic | Non-palpable breast cancer Localisation Magseed Radio frequency tag (RFID) Savi-scout reflector Wire |
| url | http://www.sciencedirect.com/science/article/pii/S2773160X24000199 |
| work_keys_str_mv | AT kumareshtimmasubramanian comparisonofthreenewwirelessnonradiationtechniquesforlocalisationofnonpalpablebreastcanceranupdatedsystematicreviewandpooledmetaanalysis AT abdolazeemelnour comparisonofthreenewwirelessnonradiationtechniquesforlocalisationofnonpalpablebreastcanceranupdatedsystematicreviewandpooledmetaanalysis AT vijaykurup comparisonofthreenewwirelessnonradiationtechniquesforlocalisationofnonpalpablebreastcanceranupdatedsystematicreviewandpooledmetaanalysis |