Animal amino acid sensor — A review

Cell growth and metabolism necessitate the involvement of amino acids, which are sensed and integrated by the mammalian target of rapamycin complex 1 (mTORC1). However, the molecular mechanisms underlying amino acid sensing remain poorly understood. Research indicates that amino acids are detected b...

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Main Authors: Yongding Ke, Xinyu Peng, Chengchuang Song, Xingtang Fang, Yanhong Wang, Chunlei Zhang
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2025-02-01
Series:Animal Bioscience
Subjects:
Online Access:http://www.animbiosci.org/upload/pdf/ab-24-0366.pdf
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author Yongding Ke
Xinyu Peng
Chengchuang Song
Xingtang Fang
Yanhong Wang
Chunlei Zhang
author_facet Yongding Ke
Xinyu Peng
Chengchuang Song
Xingtang Fang
Yanhong Wang
Chunlei Zhang
author_sort Yongding Ke
collection DOAJ
description Cell growth and metabolism necessitate the involvement of amino acids, which are sensed and integrated by the mammalian target of rapamycin complex 1 (mTORC1). However, the molecular mechanisms underlying amino acid sensing remain poorly understood. Research indicates that amino acids are detected by specific sensors, with the signals being relayed to mTORC1 indirectly. This paper reviews the structures and biological functions of the amino acid sensors identified thus far. Additionally, it evaluates the potential role these sensors play in the developmental changes of the livestock production.
format Article
id doaj-art-3b5f5bbed5714970a2f055a93b72f421
institution Kabale University
issn 2765-0189
2765-0235
language English
publishDate 2025-02-01
publisher Asian-Australasian Association of Animal Production Societies
record_format Article
series Animal Bioscience
spelling doaj-art-3b5f5bbed5714970a2f055a93b72f4212025-01-03T04:14:22ZengAsian-Australasian Association of Animal Production SocietiesAnimal Bioscience2765-01892765-02352025-02-0138219820810.5713/ab.24.036625328Animal amino acid sensor — A reviewYongding Ke0Xinyu Peng1Chengchuang Song2Xingtang Fang3Yanhong Wang4Chunlei Zhang5 School of Life Science, Jiangsu Normal University, Jiangsu 221116, China School of Life Science, Jiangsu Normal University, Jiangsu 221116, China School of Life Science, Jiangsu Normal University, Jiangsu 221116, China School of Life Science, Jiangsu Normal University, Jiangsu 221116, China School of Life Science, Jiangsu Normal University, Jiangsu 221116, China School of Life Science, Jiangsu Normal University, Jiangsu 221116, ChinaCell growth and metabolism necessitate the involvement of amino acids, which are sensed and integrated by the mammalian target of rapamycin complex 1 (mTORC1). However, the molecular mechanisms underlying amino acid sensing remain poorly understood. Research indicates that amino acids are detected by specific sensors, with the signals being relayed to mTORC1 indirectly. This paper reviews the structures and biological functions of the amino acid sensors identified thus far. Additionally, it evaluates the potential role these sensors play in the developmental changes of the livestock production.http://www.animbiosci.org/upload/pdf/ab-24-0366.pdfamino acid sensorlivestockmammalian target of rapamycin
spellingShingle Yongding Ke
Xinyu Peng
Chengchuang Song
Xingtang Fang
Yanhong Wang
Chunlei Zhang
Animal amino acid sensor — A review
Animal Bioscience
amino acid sensor
livestock
mammalian target of rapamycin
title Animal amino acid sensor — A review
title_full Animal amino acid sensor — A review
title_fullStr Animal amino acid sensor — A review
title_full_unstemmed Animal amino acid sensor — A review
title_short Animal amino acid sensor — A review
title_sort animal amino acid sensor a review
topic amino acid sensor
livestock
mammalian target of rapamycin
url http://www.animbiosci.org/upload/pdf/ab-24-0366.pdf
work_keys_str_mv AT yongdingke animalaminoacidsensorareview
AT xinyupeng animalaminoacidsensorareview
AT chengchuangsong animalaminoacidsensorareview
AT xingtangfang animalaminoacidsensorareview
AT yanhongwang animalaminoacidsensorareview
AT chunleizhang animalaminoacidsensorareview