Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States
Background: Vaginal self-collection offers an effective option for cervical cancer (CC) screening that can improve screening experiences and engagement. Objective: This article presents data from a multi-center pilot study (n = 185) across the United States, evaluating experiences and preferences re...
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| Format: | Article |
| Language: | English |
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Mary Ann Liebert
2025-01-01
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| Series: | Women's Health Reports |
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| Online Access: | https://www.liebertpub.com/doi/10.1089/whr.2025.0017 |
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| author | LaShonda Crane Ashley Jennings Megan B. Fitzpatrick Meghna Mukherjee Callie Pitchford Amy Nacht Nia’Ja Mack Kristina Krueger Jessica Favreau Kristin Conway Laura Gillis Christine Conageski Elizabeth Sutton |
| author_facet | LaShonda Crane Ashley Jennings Megan B. Fitzpatrick Meghna Mukherjee Callie Pitchford Amy Nacht Nia’Ja Mack Kristina Krueger Jessica Favreau Kristin Conway Laura Gillis Christine Conageski Elizabeth Sutton |
| author_sort | LaShonda Crane |
| collection | DOAJ |
| description | Background: Vaginal self-collection offers an effective option for cervical cancer (CC) screening that can improve screening experiences and engagement. Objective: This article presents data from a multi-center pilot study (n = 185) across the United States, evaluating experiences and preferences reported with an at-home self-collection device compared with clinician-collected screening using a speculum. The device is designed specifically for at-home self-collection and optimized for performance and usability, where collected samples are tested for high-risk human papillomavirus (hrHPV) using the Roche cobas HPV test. In an earlier report, self-collected samples using this device showed high agreement for hrHPV detection when compared with clinician-collection with a speculum and cervical brush. Study Design: Participants were screened with a self-collection device and a clinician-collection. They provided feedback about their experiences via usability and preference surveys. Results: Significantly more participants reported pain (p < 0.001), discomfort (p < 0.001), embarrassment (p < 0.001), and nervousness (p < 0.001) during clinician-collection compared with self-collection. In contrast, being at-ease (p < 0.001) and in-control (p < 0.001) were reported significantly more during self-collection. Similar patterns held across demographic groups relevant to CC screening engagement and related risk (i.e., sexual orientation, menopause status, income, and prior HPV diagnosis). Almost all (94% [156/166]) felt confident using the at-home self-collection device if they knew the results would be equivalent to clinician-collection. The device demonstrated wide usability, with 96% (163/170) successfully self-collecting using only the device’s provided instructions. Conclusion: By improving screening experiences and accessibility, at-home self-collection can increase screening participation and accelerate progress toward eliminating CC as a public health concern in the United States. |
| format | Article |
| id | doaj-art-3b4cbfecb2694e33a8edccdf9ad0d6fb |
| institution | Kabale University |
| issn | 2688-4844 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Mary Ann Liebert |
| record_format | Article |
| series | Women's Health Reports |
| spelling | doaj-art-3b4cbfecb2694e33a8edccdf9ad0d6fb2025-08-20T03:48:07ZengMary Ann LiebertWomen's Health Reports2688-48442025-01-016156457510.1089/whr.2025.0017Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United StatesLaShonda Crane0Ashley Jennings1Megan B. Fitzpatrick2Meghna Mukherjee3Callie Pitchford4Amy Nacht5Nia’Ja Mack6Kristina Krueger7Jessica Favreau8Kristin Conway9Laura Gillis10Christine Conageski11Elizabeth Sutton12Planned Parenthood Gulf Coast, Inc, Houston, Texas, USA.University of Wisconsin, Madison, Wisconsin, USA.Teal Health, Inc, San Francisco, California, USA.Teal Health, Inc, San Francisco, California, USA.Woman’s Hospital, Baton Rouge, Louisiana, USA.University of Colorado School of Medicine, Aurora, Colorado, USA.Woman’s Hospital, Baton Rouge, Louisiana, USA.University of Wisconsin, Madison, Wisconsin, USA.Crescendo, MD, Portola Valley, California, USA.Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.NxGen BioStats, LLC, Mount Airy, Maryland, USA.University of Colorado School of Medicine, Aurora, Colorado, USA.Woman’s Hospital, Baton Rouge, Louisiana, USA.Background: Vaginal self-collection offers an effective option for cervical cancer (CC) screening that can improve screening experiences and engagement. Objective: This article presents data from a multi-center pilot study (n = 185) across the United States, evaluating experiences and preferences reported with an at-home self-collection device compared with clinician-collected screening using a speculum. The device is designed specifically for at-home self-collection and optimized for performance and usability, where collected samples are tested for high-risk human papillomavirus (hrHPV) using the Roche cobas HPV test. In an earlier report, self-collected samples using this device showed high agreement for hrHPV detection when compared with clinician-collection with a speculum and cervical brush. Study Design: Participants were screened with a self-collection device and a clinician-collection. They provided feedback about their experiences via usability and preference surveys. Results: Significantly more participants reported pain (p < 0.001), discomfort (p < 0.001), embarrassment (p < 0.001), and nervousness (p < 0.001) during clinician-collection compared with self-collection. In contrast, being at-ease (p < 0.001) and in-control (p < 0.001) were reported significantly more during self-collection. Similar patterns held across demographic groups relevant to CC screening engagement and related risk (i.e., sexual orientation, menopause status, income, and prior HPV diagnosis). Almost all (94% [156/166]) felt confident using the at-home self-collection device if they knew the results would be equivalent to clinician-collection. The device demonstrated wide usability, with 96% (163/170) successfully self-collecting using only the device’s provided instructions. Conclusion: By improving screening experiences and accessibility, at-home self-collection can increase screening participation and accelerate progress toward eliminating CC as a public health concern in the United States.https://www.liebertpub.com/doi/10.1089/whr.2025.0017HPV testcervical cancer screeningat-home self-collectionspeculumexperiencespreferences |
| spellingShingle | LaShonda Crane Ashley Jennings Megan B. Fitzpatrick Meghna Mukherjee Callie Pitchford Amy Nacht Nia’Ja Mack Kristina Krueger Jessica Favreau Kristin Conway Laura Gillis Christine Conageski Elizabeth Sutton Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States Women's Health Reports HPV test cervical cancer screening at-home self-collection speculum experiences preferences |
| title | Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States |
| title_full | Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States |
| title_fullStr | Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States |
| title_full_unstemmed | Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States |
| title_short | Experiences and Preferences Reported with an At-Home Self-Collection Device Compared with In-Clinic Speculum-Based Cervical Cancer Screening in the United States |
| title_sort | experiences and preferences reported with an at home self collection device compared with in clinic speculum based cervical cancer screening in the united states |
| topic | HPV test cervical cancer screening at-home self-collection speculum experiences preferences |
| url | https://www.liebertpub.com/doi/10.1089/whr.2025.0017 |
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