PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function
Protein tyrosine phosphatases (PTPs) act as key regulators in various cellular processes such as proliferation, differentiation, and migration. Our previous research demonstrated that non-receptor-typed PTP21 (PTPN21), a member of the PTP family, played a critical role in the proliferation, cell cyc...
Saved in:
| Main Authors: | Huafang Wang, Xiaohang Ye, Haowen Xiao, Ni Zhu, Cong Wei, Xiang Sun, Limengmeng Wang, Binsheng Wang, Xiaohong Yu, Xiaoyu Lai, Shan Fu, He Huang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2019/4686132 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Mesenchymal stromal cells from people with osteoporosis are fewer, and defective in both osteogenic and adipogenic capacity
by: Féaron C. Cassidy, et al.
Published: (2024-06-01) -
Loss of PTPN21 disrupted mitochondrial metabolic homeostasis and aggravated experimental pulmonary fibrosis
by: Hui Lian, et al.
Published: (2024-12-01) -
Research progress on the effect and mechanism of immune cells on osteogenic differentiation of bone marrow mesenchymal stem cells
by: SHI Yan, et al.
Published: (2024-04-01) -
miR-144-3p targeting FLRT3 in osteogenic differentiation of mandibular bone marrow mesenchymal stem cells
by: Jingjun Tian, et al.
Published: (2025-07-01) -
Recent advances of SNHG in regulating mesenchymal stem cell osteogenic differentiation
by: HUANG Jie, et al.
Published: (2024-08-01)