Comparable immunogenicity of new modality biotherapeutics delivered subcutaneously or intravenously in non-human primates

Unwanted immunogenicity of therapeutic proteins arises through the combination of many factors, with the route of administration considered a significant contributor. Contrary to historic data on vaccine delivery, analysis of various therapeutic protein products indicates that the subcutaneous route...

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Bibliographic Details
Main Authors: Victoria Koch, Martin Lechmann, Katharine Bray-French, Matthias Füth, Elisabeth Husar, Niels Janssen, Anneliese Schneider, Kay Stubenrauch, Timothy Hickling, Sven Kronenberg
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Immunotoxicology
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Online Access:https://www.tandfonline.com/doi/10.1080/1547691X.2025.2537408
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