Adrenal mass: Unusual presentation and outcome

Aim: Adrenal mass may be functioning or nonfunctioning with varied clinical presentations. This study aimed to report the nature and management of uncommon adrenal mass and to review literature. Materials and Methods: This was an retrospective observational analysis of children with uncommon adrenal...

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Main Authors: Raghu Sampally Ramareddy, Anand Alladi
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2017-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2017;volume=38;issue=3;spage=256;epage=260;aulast=Ramareddy
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author Raghu Sampally Ramareddy
Anand Alladi
author_facet Raghu Sampally Ramareddy
Anand Alladi
author_sort Raghu Sampally Ramareddy
collection DOAJ
description Aim: Adrenal mass may be functioning or nonfunctioning with varied clinical presentations. This study aimed to report the nature and management of uncommon adrenal mass and to review literature. Materials and Methods: This was an retrospective observational analysis of children with uncommon adrenal mass admitted during 2009–2015. Clinical features, investigations, and management of patients were analyzed. Results: Among six, two each were adolescent and neonate, and one each was young infant and prenatal. Clinical presentation was variable; hypertensive retinopathy,[1] virilization[1] and bleeding diathesis,[1] antenatal suprarenal mass,[1] prenatal adrenal angiolipoma,[1] and spontaneous resolution of Stage III suprarenal mass.[1] Ultrasound and contrast-enhanced computed tomography revealed well-defined, heterogeneous adrenal mass. Size varied from 2 to 15 cm. Urinary metanephrine and serum testosterone were raised in adolescent hypertensive boys and virilized girls, respectively. Laparoscopy-assisted adrenalectomy was done in two and other four were managed conservatively. Histopathology of tumor revealed pheochromocytoma and borderline oncocytoma. Spontaneous resolution of adrenal mass had varied etiology; adrenal hemorrhagic lesion,[1] simple cyst,[1] neuroblastoma.[1] Follow-up varied from 3 months to 2 years. All patients were asymptomatic on last follow-up. Conclusion: Close clinical follow-up, contrast-enhanced tomography, and limited/specific endocrine work-up have definite role in the management of uncommon adrenal mass.
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spelling doaj-art-3ad57cdf74e34b1d8dc3b51c8dc658f72025-08-20T01:56:33ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512017-01-0138325626010.4103/ijmpo.ijmpo_33_16Adrenal mass: Unusual presentation and outcomeRaghu Sampally RamareddyAnand AlladiAim: Adrenal mass may be functioning or nonfunctioning with varied clinical presentations. This study aimed to report the nature and management of uncommon adrenal mass and to review literature. Materials and Methods: This was an retrospective observational analysis of children with uncommon adrenal mass admitted during 2009–2015. Clinical features, investigations, and management of patients were analyzed. Results: Among six, two each were adolescent and neonate, and one each was young infant and prenatal. Clinical presentation was variable; hypertensive retinopathy,[1] virilization[1] and bleeding diathesis,[1] antenatal suprarenal mass,[1] prenatal adrenal angiolipoma,[1] and spontaneous resolution of Stage III suprarenal mass.[1] Ultrasound and contrast-enhanced computed tomography revealed well-defined, heterogeneous adrenal mass. Size varied from 2 to 15 cm. Urinary metanephrine and serum testosterone were raised in adolescent hypertensive boys and virilized girls, respectively. Laparoscopy-assisted adrenalectomy was done in two and other four were managed conservatively. Histopathology of tumor revealed pheochromocytoma and borderline oncocytoma. Spontaneous resolution of adrenal mass had varied etiology; adrenal hemorrhagic lesion,[1] simple cyst,[1] neuroblastoma.[1] Follow-up varied from 3 months to 2 years. All patients were asymptomatic on last follow-up. Conclusion: Close clinical follow-up, contrast-enhanced tomography, and limited/specific endocrine work-up have definite role in the management of uncommon adrenal mass.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2017;volume=38;issue=3;spage=256;epage=260;aulast=RamareddyAdrenal massbleeding diathesishypertensiononcocytomavirilize
spellingShingle Raghu Sampally Ramareddy
Anand Alladi
Adrenal mass: Unusual presentation and outcome
Indian Journal of Medical and Paediatric Oncology
Adrenal mass
bleeding diathesis
hypertension
oncocytoma
virilize
title Adrenal mass: Unusual presentation and outcome
title_full Adrenal mass: Unusual presentation and outcome
title_fullStr Adrenal mass: Unusual presentation and outcome
title_full_unstemmed Adrenal mass: Unusual presentation and outcome
title_short Adrenal mass: Unusual presentation and outcome
title_sort adrenal mass unusual presentation and outcome
topic Adrenal mass
bleeding diathesis
hypertension
oncocytoma
virilize
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2017;volume=38;issue=3;spage=256;epage=260;aulast=Ramareddy
work_keys_str_mv AT raghusampallyramareddy adrenalmassunusualpresentationandoutcome
AT anandalladi adrenalmassunusualpresentationandoutcome