Positive end-expiratory pressure increases intracranial pressure but not pressure reactivity index in supine and prone positions: a porcine model study

Positive end-expiratory pressure increases intracranial pressure but not pressure reactivity index in supine and prone positions: a porcine model study

IntroductionPositive end-expiratory pressure (PEEP) and prone positioning can improve gas exchange by promoting uniform lung aeration. However, elevated ventilation pressures may increase intracranial pressure (ICP) and disrupt cerebral autoregulation. This study investigated the effects of PEEP on...

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Bibliographic Details
Main Authors: Rønnaug Hammervold, Erta Beqiri, Peter Smielewski, Benjamin S. Storm, Erik W. Nielsen, Claude Guérin, Shirin K. Frisvold
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
cerebral autoregulation
ICP
neurocritical care
neuromonitoring
pulmonary issues
ventilation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1501284/full
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