Temperature induces brain-intake shift of recombinant high-density lipoprotein after traumatic brain injury

Temperature induces brain-intake shift of recombinant high-density lipoprotein after traumatic brain injury

Abstract Traumatic brain injury (TBI) is one of the leading public health concerns in the world. Therapeutic hypothermia is routinely used in severe TBI, and pathophysiological hyperthermia, frequently observed in TBI patients, has an unclear impact on drug transport in the injured brain due to a la...

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Bibliographic Details
Main Authors: Jialin Huang, Yidong Peng, Xin Wang, Xiaokun Gu, Yao Yi, Wenye Wang, Zhenghui He, Zixuan Ma, Qiyuan Feng, Wenlan Qi, Jiyuan Hui, Ru Gong, Weiji Weng, Gan Jiang, Yingwei Gao, Yong Lin, Jin Li, Jiyao Jiang, Junfeng Feng
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Mild hypothermia
Hyperthermia
Pharmacotherapy
Cellular uptake
Brain transport
Online Access:https://doi.org/10.1186/s12951-024-03016-z
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