How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study

Abstract Background Endometriosis (EMS) and chronic endometritis (CE) frequently coexist. This study aimed to examine the impact of CE on reproductive outcomes in patients with EMS. Methods We enrolled 685 patients with endometriosis-associated infertility from January 2018 to December 2020. The pat...

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Main Authors: Shunhe Lin, Xi Xie, Yishan Chen, Zhenna Wang, Jinna Zhang, Chaobin Liu, Guan Lin, Yi Wang, Yuyan Guo
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Reproductive Health
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Online Access:https://doi.org/10.1186/s12978-024-01897-9
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author Shunhe Lin
Xi Xie
Yishan Chen
Zhenna Wang
Jinna Zhang
Chaobin Liu
Guan Lin
Yi Wang
Yuyan Guo
author_facet Shunhe Lin
Xi Xie
Yishan Chen
Zhenna Wang
Jinna Zhang
Chaobin Liu
Guan Lin
Yi Wang
Yuyan Guo
author_sort Shunhe Lin
collection DOAJ
description Abstract Background Endometriosis (EMS) and chronic endometritis (CE) frequently coexist. This study aimed to examine the impact of CE on reproductive outcomes in patients with EMS. Methods We enrolled 685 patients with endometriosis-associated infertility from January 2018 to December 2020. The patients were divided into CE (318) and non-CE (367) groups. A subset of 123 clinically pregnant women from the CE group and 369 from the non-CE group was selected for detailed comparison. Pregnancy and delivery data were meticulously collected from hospital records and through telephone interviews. Results CE was diagnosed in 46.42% of EMS patients. Higher pregnancy rates were observed in patients with Endometriosis Fertility Index (EFI) scores of 7–10. EMS patients with CE had increased risks of placenta previa (13.01%), gestational hypertension (5.69%), and cesarean sections (59.34%). Conclusions CE, which is prevalent among EMS patients, is linked to increased risks of pregnancy complications, including placenta previa, gestational hypertension, and cesarean delivery. Although combined hysteroscopy and laparoscopy improve pregnancy rates, they demand careful management of these complications.
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institution Kabale University
issn 1742-4755
language English
publishDate 2024-11-01
publisher BMC
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series Reproductive Health
spelling doaj-art-3aba0c24e4f04fd3af75e73251e4e6c62024-11-17T12:31:24ZengBMCReproductive Health1742-47552024-11-0121111110.1186/s12978-024-01897-9How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort studyShunhe Lin0Xi Xie1Yishan Chen2Zhenna Wang3Jinna Zhang4Chaobin Liu5Guan Lin6Yi Wang7Yuyan Guo8Department of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityDepartment of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, College of Clinical Medical for Obstetrics & Gynecology and Pediatrics, Fujian Medical UniversityPhysical Examination Center, Fujian Medical University Union HospitalAbstract Background Endometriosis (EMS) and chronic endometritis (CE) frequently coexist. This study aimed to examine the impact of CE on reproductive outcomes in patients with EMS. Methods We enrolled 685 patients with endometriosis-associated infertility from January 2018 to December 2020. The patients were divided into CE (318) and non-CE (367) groups. A subset of 123 clinically pregnant women from the CE group and 369 from the non-CE group was selected for detailed comparison. Pregnancy and delivery data were meticulously collected from hospital records and through telephone interviews. Results CE was diagnosed in 46.42% of EMS patients. Higher pregnancy rates were observed in patients with Endometriosis Fertility Index (EFI) scores of 7–10. EMS patients with CE had increased risks of placenta previa (13.01%), gestational hypertension (5.69%), and cesarean sections (59.34%). Conclusions CE, which is prevalent among EMS patients, is linked to increased risks of pregnancy complications, including placenta previa, gestational hypertension, and cesarean delivery. Although combined hysteroscopy and laparoscopy improve pregnancy rates, they demand careful management of these complications.https://doi.org/10.1186/s12978-024-01897-9Chronic endometritisEndometriosisInfertilityReproductive outcomesLaparoscopy
spellingShingle Shunhe Lin
Xi Xie
Yishan Chen
Zhenna Wang
Jinna Zhang
Chaobin Liu
Guan Lin
Yi Wang
Yuyan Guo
How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study
Reproductive Health
Chronic endometritis
Endometriosis
Infertility
Reproductive outcomes
Laparoscopy
title How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study
title_full How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study
title_fullStr How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study
title_full_unstemmed How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study
title_short How does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility? A retrospective cohort study
title_sort how does chronic endometritis influence pregnancy outcomes in endometriosis associated infertility a retrospective cohort study
topic Chronic endometritis
Endometriosis
Infertility
Reproductive outcomes
Laparoscopy
url https://doi.org/10.1186/s12978-024-01897-9
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