Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand

In this work, we present the design and synthesis of the <i>bis</i>thiosemicarbazone ligand H<sub>3</sub>L<sup>Me</sup> by means of an iminic condensation reaction between 2-hydroxyisophthalaldehyde and 4-methyl-3-thiosemicarbazide. This ligand is bicompartmental,...

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Bibliographic Details
Main Authors: Isabel Velo-Heleno, Sandra Fernández-Fariña, Uxía Barreiro-Sisto, Laura Rodríguez-Silva, Rosa Pedrido
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Chemistry Proceedings
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Online Access:https://www.mdpi.com/2673-4583/14/1/39
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Summary:In this work, we present the design and synthesis of the <i>bis</i>thiosemicarbazone ligand H<sub>3</sub>L<sup>Me</sup> by means of an iminic condensation reaction between 2-hydroxyisophthalaldehyde and 4-methyl-3-thiosemicarbazide. This ligand is bicompartmental, pentadentate [N<sub>2</sub>S<sub>2</sub>O] and potentially trianionic. The presence of a spacer constituted by a phenol group facilitates the coordination of transition metal ions, giving rise to a great variety of structures. To confirm the purity of the ligand, different characterization techniques were employed, including elemental analysis, mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance. The acquisition of suitable crystals of H<sub>3</sub>L<sup>Me</sup> allowed us to analyze its structure through X-ray diffraction studies.
ISSN:2673-4583