Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report
Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and t...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Urology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442024002560 |
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| author | Yuchong Qiu Sicheng Wu Jianyang Lv Zhigang Ji Jie Dong |
| author_facet | Yuchong Qiu Sicheng Wu Jianyang Lv Zhigang Ji Jie Dong |
| author_sort | Yuchong Qiu |
| collection | DOAJ |
| description | Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and transurethral resection of the mass was performed. Interestingly, the histopathology of the excised mass showed pink-staining material under Hematoxylin and Eosin staining, but negative Congo red staining. This case demonstrates that a negative Congo red staining doesn't exclude amyloidosis. An accurate diagnosis should rely on a comprehensive evaluation of clinical, laboratory, radiological, and histopathological findings. |
| format | Article |
| id | doaj-art-3a51fe5f9e7945a6baaaa8f5a8d4d7f8 |
| institution | Kabale University |
| issn | 2214-4420 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj-art-3a51fe5f9e7945a6baaaa8f5a8d4d7f82025-01-14T04:12:19ZengElsevierUrology Case Reports2214-44202025-01-0158102902Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case reportYuchong Qiu0Sicheng Wu1Jianyang Lv2Zhigang Ji3Jie Dong4Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; 4+4 Medical Doctor Program, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaDepartment of Urology, Beijing No.6 Hospital, Beijing, ChinaDepartment of Urology, Beijing No.6 Hospital, Beijing, ChinaDepartment of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaDepartment of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Corresponding author.Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and transurethral resection of the mass was performed. Interestingly, the histopathology of the excised mass showed pink-staining material under Hematoxylin and Eosin staining, but negative Congo red staining. This case demonstrates that a negative Congo red staining doesn't exclude amyloidosis. An accurate diagnosis should rely on a comprehensive evaluation of clinical, laboratory, radiological, and histopathological findings.http://www.sciencedirect.com/science/article/pii/S2214442024002560Congo red stainingLocalized bladder amyloidosisPink-staining material |
| spellingShingle | Yuchong Qiu Sicheng Wu Jianyang Lv Zhigang Ji Jie Dong Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report Urology Case Reports Congo red staining Localized bladder amyloidosis Pink-staining material |
| title | Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report |
| title_full | Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report |
| title_fullStr | Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report |
| title_full_unstemmed | Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report |
| title_short | Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report |
| title_sort | primary localized bladder amyloidosis with negative postoperative congo red staining a case report |
| topic | Congo red staining Localized bladder amyloidosis Pink-staining material |
| url | http://www.sciencedirect.com/science/article/pii/S2214442024002560 |
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