Primary localized bladder amyloidosis with negative postoperative Congo red staining: A case report
Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442024002560 |
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| Summary: | Localized bladder amyloidosis is a rare disorder mimicking bladder tumor, with merely over 200 reported cases. Here, we report a case of a 67-year-old female presented with painless gross hematuria. A positive Congo red staining of the cystoscopy biopsy raised suspicion of bladder amyloidosis, and transurethral resection of the mass was performed. Interestingly, the histopathology of the excised mass showed pink-staining material under Hematoxylin and Eosin staining, but negative Congo red staining. This case demonstrates that a negative Congo red staining doesn't exclude amyloidosis. An accurate diagnosis should rely on a comprehensive evaluation of clinical, laboratory, radiological, and histopathological findings. |
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| ISSN: | 2214-4420 |