Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana

Antimony (Sb) is a toxic pollutant, with Sb(V) being one of its main forms in the environment, but the process and mechanism of plant uptake of Sb(V) remain unclear. To investigate the process of Sb(V) uptake by plants, Arabidopsis thaliana plants were exposed to water culture media supplemented wit...

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Main Authors: Ziyi Dong, Mengchang He, Chunye Lin, Wei Ouyang, Xitao Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324014477
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_version_ 1846138592104022016
author Ziyi Dong
Mengchang He
Chunye Lin
Wei Ouyang
Xitao Liu
author_facet Ziyi Dong
Mengchang He
Chunye Lin
Wei Ouyang
Xitao Liu
author_sort Ziyi Dong
collection DOAJ
description Antimony (Sb) is a toxic pollutant, with Sb(V) being one of its main forms in the environment, but the process and mechanism of plant uptake of Sb(V) remain unclear. To investigate the process of Sb(V) uptake by plants, Arabidopsis thaliana plants were exposed to water culture media supplemented with different Sb(V) concentrations. The distribution, content, and forms of Sb(V) in Arabidopsis roots, and the accumulation and fixation of Sb(V) in Arabidopsis plants were studied. In addition, inhibitor experiments and analyses of gene expression changes were conducted to elucidate the underlying mechanism of its toxicity. Sb(V) entering the roots was mainly adsorbed on the cell wall, and the Sb(V) content in both apoplastic solution and symplastic solution increased with increasing external Sb(V) concentration. Sb(V) concentration in apoplast and symplast were approximately linearly correlated (R2=0.980), indicating low affinity of cells for Sb(V) absorption. Moreover, uncouplers significantly inhibited the entry of Sb(V) into the symplast, suggesting that the transmembrane transport of Sb(V) is energy-consuming. Sb(V) entering the cell could be partially reduced to Sb(III), and significant changes in glutathione metabolism gene expression were detected, indicating the important role of glutathione metabolism in the detoxification of Sb(V). From the perspective of the whole plant, although Sb(V) is absorbed by the roots, it is mainly fixed in the leaves and stems. This study revealed the pattern of Sb(V) uptake by plants and elucidated the mechanism of Sb(V) uptake by plants from the perspectives of kinetics, physiology, and genetics.
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spelling doaj-art-3a44e13aa8cd43cd98ef33938a8f32392024-12-07T08:24:33ZengElsevierEcotoxicology and Environmental Safety0147-65132024-12-01288117371Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thalianaZiyi Dong0Mengchang He1Chunye Lin2Wei Ouyang3Xitao Liu4State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, ChinaState Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China; Corresponding author.State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, ChinaState Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China; Advanced Interdisciplinary Institute of Environment and Ecology, Beijing Normal University, Zhuhai 519087, ChinaState Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, ChinaAntimony (Sb) is a toxic pollutant, with Sb(V) being one of its main forms in the environment, but the process and mechanism of plant uptake of Sb(V) remain unclear. To investigate the process of Sb(V) uptake by plants, Arabidopsis thaliana plants were exposed to water culture media supplemented with different Sb(V) concentrations. The distribution, content, and forms of Sb(V) in Arabidopsis roots, and the accumulation and fixation of Sb(V) in Arabidopsis plants were studied. In addition, inhibitor experiments and analyses of gene expression changes were conducted to elucidate the underlying mechanism of its toxicity. Sb(V) entering the roots was mainly adsorbed on the cell wall, and the Sb(V) content in both apoplastic solution and symplastic solution increased with increasing external Sb(V) concentration. Sb(V) concentration in apoplast and symplast were approximately linearly correlated (R2=0.980), indicating low affinity of cells for Sb(V) absorption. Moreover, uncouplers significantly inhibited the entry of Sb(V) into the symplast, suggesting that the transmembrane transport of Sb(V) is energy-consuming. Sb(V) entering the cell could be partially reduced to Sb(III), and significant changes in glutathione metabolism gene expression were detected, indicating the important role of glutathione metabolism in the detoxification of Sb(V). From the perspective of the whole plant, although Sb(V) is absorbed by the roots, it is mainly fixed in the leaves and stems. This study revealed the pattern of Sb(V) uptake by plants and elucidated the mechanism of Sb(V) uptake by plants from the perspectives of kinetics, physiology, and genetics.http://www.sciencedirect.com/science/article/pii/S0147651324014477AntimonySb(V)Arabidopsis thalianaUptakeAccumulationGene response
spellingShingle Ziyi Dong
Mengchang He
Chunye Lin
Wei Ouyang
Xitao Liu
Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
Ecotoxicology and Environmental Safety
Antimony
Sb(V)
Arabidopsis thaliana
Uptake
Accumulation
Gene response
title Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
title_full Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
title_fullStr Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
title_full_unstemmed Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
title_short Uptake, accumulation and gene response of Sb(Ⅴ) in Arabidopsis thaliana
title_sort uptake accumulation and gene response of sb v in arabidopsis thaliana
topic Antimony
Sb(V)
Arabidopsis thaliana
Uptake
Accumulation
Gene response
url http://www.sciencedirect.com/science/article/pii/S0147651324014477
work_keys_str_mv AT ziyidong uptakeaccumulationandgeneresponseofsbvinarabidopsisthaliana
AT mengchanghe uptakeaccumulationandgeneresponseofsbvinarabidopsisthaliana
AT chunyelin uptakeaccumulationandgeneresponseofsbvinarabidopsisthaliana
AT weiouyang uptakeaccumulationandgeneresponseofsbvinarabidopsisthaliana
AT xitaoliu uptakeaccumulationandgeneresponseofsbvinarabidopsisthaliana