An optimized approach to study nanoscale sarcomere structure utilizing super-resolution microscopy with nanobodies.
The sarcomere is the fundamental contractile unit in skeletal muscle, and the regularity of its structure is critical for function. Emerging data demonstrates that nanoscale changes to the regularity of sarcomere structure can affect the overall function of the protein dense ~2μm sarcomere. Further,...
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| Main Authors: | Collin M Douglas, Jonathan E Bird, Daniel Kopinke, Karyn A Esser |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0300348&type=printable |
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