Ascites of unknown origin in infant: a rare case report
Introduction. Ascites of unknown origin in infants are rare and diagnostically challenging. However, it can be associated with a poor prognosis if it is not treated promptly. Case presentation. A 3-month-old boy infant was admitted to the Dr. Soetomo General Academic Hospital, Surabaya because of a...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2024-09-01
|
| Series: | Romanian Journal of Pediatrics |
| Subjects: | |
| Online Access: | https://rjp.com.ro/articles/2024.3/RJP_2024_3_Art-09.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846124718907719680 |
|---|---|
| author | Rendi Aji Prihaningtyas Bagus Setyoboedi Faradila Khoirun Nisa Hakim Sjamsul Arief |
| author_facet | Rendi Aji Prihaningtyas Bagus Setyoboedi Faradila Khoirun Nisa Hakim Sjamsul Arief |
| author_sort | Rendi Aji Prihaningtyas |
| collection | DOAJ |
| description | Introduction. Ascites of unknown origin in infants are rare and diagnostically challenging. However, it can be associated with a poor prognosis if it is not treated promptly. Case presentation. A 3-month-old boy infant was admitted to the Dr. Soetomo General Academic Hospital, Surabaya because of a 2-week history of progressive abdominal distension with massive ascites following fever onset. Laboratory parameter measurement revealed increased liver function test, hypoalbuminemia, and prolonged coagulation factor. Hepatitis markers were negative. TORCH serological examination showed non-reactive. Urinalysis, renal function test, and echocardiography were normal. The ascitic fluid analysis showed SAAG >1.1 g/dL. An abdominal ultrasound examination revealed ascites. MRCP showed hepatomegaly and ascites. A liver biopsy showed foci of polymorphonuclear and mononuclear inflammatory cell distribution among hepatocytes with no hepatic fibrosis. He was treated with antibiotics, steroids, diuretics, and albumin transfusion. There were no ascites and laboratory parameters were improved after treatment. Conclusion. Progressive and rapid hepatic inflammatory mechanisms may play a role in the development of ascites. Steroids may be considered in cases of unexplained ascites thought to be related to liver injury to prevent further liver fibrosis. |
| format | Article |
| id | doaj-art-39d4c85f24ee454e87ca66fbd272e16f |
| institution | Kabale University |
| issn | 1454-0398 2069-6175 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Pediatrics |
| spelling | doaj-art-39d4c85f24ee454e87ca66fbd272e16f2024-12-13T14:07:20ZengAmaltea Medical Publishing HouseRomanian Journal of Pediatrics1454-03982069-61752024-09-0173318619210.37897/RJP.2024.3.9Ascites of unknown origin in infant: a rare case reportRendi Aji Prihaningtyas0Bagus Setyoboedi1Faradila Khoirun Nisa Hakim2Sjamsul Arief3Department of Child Health, Faculty of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Department of Child Health, Faculty of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Department of Child Health, Faculty of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaDepartment of Child Health, Faculty of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Introduction. Ascites of unknown origin in infants are rare and diagnostically challenging. However, it can be associated with a poor prognosis if it is not treated promptly. Case presentation. A 3-month-old boy infant was admitted to the Dr. Soetomo General Academic Hospital, Surabaya because of a 2-week history of progressive abdominal distension with massive ascites following fever onset. Laboratory parameter measurement revealed increased liver function test, hypoalbuminemia, and prolonged coagulation factor. Hepatitis markers were negative. TORCH serological examination showed non-reactive. Urinalysis, renal function test, and echocardiography were normal. The ascitic fluid analysis showed SAAG >1.1 g/dL. An abdominal ultrasound examination revealed ascites. MRCP showed hepatomegaly and ascites. A liver biopsy showed foci of polymorphonuclear and mononuclear inflammatory cell distribution among hepatocytes with no hepatic fibrosis. He was treated with antibiotics, steroids, diuretics, and albumin transfusion. There were no ascites and laboratory parameters were improved after treatment. Conclusion. Progressive and rapid hepatic inflammatory mechanisms may play a role in the development of ascites. Steroids may be considered in cases of unexplained ascites thought to be related to liver injury to prevent further liver fibrosis.https://rjp.com.ro/articles/2024.3/RJP_2024_3_Art-09.pdfascitesabdominal distensionhepatic fibrosis |
| spellingShingle | Rendi Aji Prihaningtyas Bagus Setyoboedi Faradila Khoirun Nisa Hakim Sjamsul Arief Ascites of unknown origin in infant: a rare case report Romanian Journal of Pediatrics ascites abdominal distension hepatic fibrosis |
| title | Ascites of unknown origin in infant: a rare case report |
| title_full | Ascites of unknown origin in infant: a rare case report |
| title_fullStr | Ascites of unknown origin in infant: a rare case report |
| title_full_unstemmed | Ascites of unknown origin in infant: a rare case report |
| title_short | Ascites of unknown origin in infant: a rare case report |
| title_sort | ascites of unknown origin in infant a rare case report |
| topic | ascites abdominal distension hepatic fibrosis |
| url | https://rjp.com.ro/articles/2024.3/RJP_2024_3_Art-09.pdf |
| work_keys_str_mv | AT rendiajiprihaningtyas ascitesofunknownoriginininfantararecasereport AT bagussetyoboedi ascitesofunknownoriginininfantararecasereport AT faradilakhoirunnisahakim ascitesofunknownoriginininfantararecasereport AT sjamsularief ascitesofunknownoriginininfantararecasereport |