Communication between DNA polymerases and Replication Protein A within the archaeal replisome

Communication between DNA polymerases and Replication Protein A within the archaeal replisome

Abstract Replication Protein A (RPA) plays a pivotal role in DNA replication by coating and protecting exposed single-stranded DNA, and acting as a molecular hub that recruits additional replication factors. We demonstrate that archaeal RPA hosts a winged-helix domain (WH) that interacts with two ke...

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Bibliographic Details
Main Authors: Markel Martínez-Carranza, Léa Vialle, Clément Madru, Florence Cordier, Ayten Dizkirici Tekpinar, Ahmed Haouz, Pierre Legrand, Rémy A. Le Meur, Patrick England, Rémi Dulermo, J. Iñaki Guijarro, Ghislaine Henneke, Ludovic Sauguet
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55365-w
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