Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study
Objective: To evaluate the association between dynapenic abdominal obesity (DAO) and the following negative outcomes in older patients with type 2 diabetes (T2D): prolonged length of stay (LOS), readmission within 30 days, in-hospital mortality, and mortality within 1 year after hospital discharge....
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| Language: | English |
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Brazilian Society of Geriatrics and Gerontology
2025-01-01
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| Series: | Geriatrics, Gerontology and Aging |
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| Online Access: | https://cdn.publisher.gn1.link/ggaging.com/pdf/v18230.pdf |
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| author | Mileni Vanti Beretta Ticiana da Costa Rodrigues Thais Steemburgo |
| author_facet | Mileni Vanti Beretta Ticiana da Costa Rodrigues Thais Steemburgo |
| author_sort | Mileni Vanti Beretta |
| collection | DOAJ |
| description | Objective: To evaluate the association between dynapenic abdominal obesity (DAO) and the following negative outcomes in older patients with type 2 diabetes (T2D): prolonged length of stay (LOS), readmission within 30 days, in-hospital mortality, and mortality within 1 year after hospital discharge. Methods: This prospective cohort study included hospitalized older patients with T2D. DAO was defined as a combination of abdominal obesity (high waist circumference [WC]: ≥ 102 cm for men and ≥ 88 cm for women]) and dynapenia (reduced hand grip strength [HGS]: < ≤27 kg for men and < 16 kg for women]). The association between clinical outcomes and DAO was evaluated using multivariate analyses adjusted for confounders. The Kaplan-Meier curve was used to compare 1-year survival in the presence of DAO. Results: We included 309 patients with T2D (mean age 73.3 ± 6.4 years; 50.5% female; 32.4% with DAO). In multivariate analyses, patients with DAO had a 5.29- and 4.71-fold increase in LOS (≥ 14 days) and 1-year mortality than those without DAO, respectively. Moreover, patients with DAO had a higher risk of 1-year mortality (log-rank test, p < 0.05). Conclusions: Older patients with T2D and DAO are more likely to have prolonged hospitalization and 1-year mortality compared to those without DAO. |
| format | Article |
| id | doaj-art-394e60032c754b7da308fb311403a442 |
| institution | Kabale University |
| issn | 2447-2123 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Brazilian Society of Geriatrics and Gerontology |
| record_format | Article |
| series | Geriatrics, Gerontology and Aging |
| spelling | doaj-art-394e60032c754b7da308fb311403a4422025-01-09T11:30:43ZengBrazilian Society of Geriatrics and GerontologyGeriatrics, Gerontology and Aging2447-21232025-01-01181910.53886/gga.e0000230_ENDynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort studyMileni Vanti Beretta0https://orcid.org/0000-0002-9246-1562Ticiana da Costa Rodrigues1https://orcid.org/0000-0001-9254-3712Thais Steemburgo2https://orcid.org/0000-0003-3351-9901Universidade Federal do Rio Grande do Sul – Porto Alegre (RS), Brazil.Universidade Federal do Rio Grande do Sul – Porto Alegre (RS), Brazil.Universidade Federal do Rio Grande do Sul – Porto Alegre (RS), Brazil.Objective: To evaluate the association between dynapenic abdominal obesity (DAO) and the following negative outcomes in older patients with type 2 diabetes (T2D): prolonged length of stay (LOS), readmission within 30 days, in-hospital mortality, and mortality within 1 year after hospital discharge. Methods: This prospective cohort study included hospitalized older patients with T2D. DAO was defined as a combination of abdominal obesity (high waist circumference [WC]: ≥ 102 cm for men and ≥ 88 cm for women]) and dynapenia (reduced hand grip strength [HGS]: < ≤27 kg for men and < 16 kg for women]). The association between clinical outcomes and DAO was evaluated using multivariate analyses adjusted for confounders. The Kaplan-Meier curve was used to compare 1-year survival in the presence of DAO. Results: We included 309 patients with T2D (mean age 73.3 ± 6.4 years; 50.5% female; 32.4% with DAO). In multivariate analyses, patients with DAO had a 5.29- and 4.71-fold increase in LOS (≥ 14 days) and 1-year mortality than those without DAO, respectively. Moreover, patients with DAO had a higher risk of 1-year mortality (log-rank test, p < 0.05). Conclusions: Older patients with T2D and DAO are more likely to have prolonged hospitalization and 1-year mortality compared to those without DAO.https://cdn.publisher.gn1.link/ggaging.com/pdf/v18230.pdfabdominal obesityolder adultstype 2 diabetes |
| spellingShingle | Mileni Vanti Beretta Ticiana da Costa Rodrigues Thais Steemburgo Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study Geriatrics, Gerontology and Aging abdominal obesity older adults type 2 diabetes |
| title | Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study |
| title_full | Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study |
| title_fullStr | Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study |
| title_full_unstemmed | Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study |
| title_short | Dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes: a prospective cohort study |
| title_sort | dynapenic abdominal obesity is associated with negative clinical outcomes in older patients with type 2 diabetes a prospective cohort study |
| topic | abdominal obesity older adults type 2 diabetes |
| url | https://cdn.publisher.gn1.link/ggaging.com/pdf/v18230.pdf |
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