Annexin V–CLIO: A Nanoparticle for Detecting Apoptosis by MRI
Annexin V, which recognizes the phosphatidylserine of apoptotic cells, was conjugated to crosslinked iron oxide (CLIO) nanoparticles, a functionalized superparamagnetic preparation developed for target-specific magnetic resonance imaging (MRI). The resulting nanoparticle had an average of 2.7 annexi...
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Main Authors: | Eyk A. Schellenberger, Alexei Bogdanov, Dagmar Högemann, Jonathan Tait, Ralph Weissleder, Lee Josephson |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2002-04-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1162/15353500200202103 |
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