Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols

Social stress is the most significant source of chronic stress in humans and is commonly associated with health impairment. Individual differences in the behavioral coping responses to stress have been proposed to mediate the negative effects of stress on physical, behavioral and mental health. Anim...

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Main Authors: Alina Díez-Solinska, Zurine De Miguel, Garikoitz Azkona, Oscar Vegas
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Neurobiology of Stress
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352289524000857
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author Alina Díez-Solinska
Zurine De Miguel
Garikoitz Azkona
Oscar Vegas
author_facet Alina Díez-Solinska
Zurine De Miguel
Garikoitz Azkona
Oscar Vegas
author_sort Alina Díez-Solinska
collection DOAJ
description Social stress is the most significant source of chronic stress in humans and is commonly associated with health impairment. Individual differences in the behavioral coping responses to stress have been proposed to mediate the negative effects of stress on physical, behavioral and mental health. Animal models, particularly mice, offer valuable insights into the physiological and neurobiological correlates of behavioral coping strategies in response to chronic social stress. Here we aim to identify differences and similarities among stress protocols in mice, with particular attention to how neuroendocrine and/or behavioral responses vary according to different coping strategies, while highlighting the need for standardized approaches in future research. A systematic review was undertaken following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA statement). A total of 213 references were identified by electronic search, and after the screening, 18 articles were found to meet all the established criteria. We analyzed differences in the stress protocol, the characterization and classification of coping strategies and the physiological and behavioral differences according to coping. The results show that differences in behavioural expression under chronic social stress (coping) may also be associated with physiological differences and differential susceptibility to disease. However, this review also underlines the importance of a cautious interpretation of the results obtained. The lack of consistency in the nomenclature and procedures associated with the study of coping strategies for social stress, as well as the absence of a uniform classification, highlight the importance of using a common language when approaching the study of coping strategies. Thereby, this review encourages the development of a more defined method and criteria for assessing coping strategies, based on both behavioral and biological indicators.
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spelling doaj-art-390b2b357aed4f18a462adc7a47cdc332024-11-30T07:10:38ZengElsevierNeurobiology of Stress2352-28952024-11-0133100689Behavioral coping with chronic defeat stress in mice: A systematic review of current protocolsAlina Díez-Solinska0Zurine De Miguel1Garikoitz Azkona2Oscar Vegas3Department of Basic Psychological Processes and Their Development, University of the Basque Country UPV/EHU, 20018, Donostia-San Sebastian, SpainDepartment of Psychology, California State University, Monterey Bay, CA, USA; Department of Health Sciences, Public University of Navarre UPNA, 31006, Pamplona, SpainDepartment of Basic Psychological Processes and Their Development, University of the Basque Country UPV/EHU, 20018, Donostia-San Sebastian, SpainDepartment of Basic Psychological Processes and Their Development, University of the Basque Country UPV/EHU, 20018, Donostia-San Sebastian, Spain; Biogipuzkoa Health Research Institute, 20014, Donostia-San Sebastian, Spain; Corresponding author. Department of Basic Psychological Processes and their Development, University of the Basque Country, Avda. Tolosa 70, Donostia, 20018, Spain.Social stress is the most significant source of chronic stress in humans and is commonly associated with health impairment. Individual differences in the behavioral coping responses to stress have been proposed to mediate the negative effects of stress on physical, behavioral and mental health. Animal models, particularly mice, offer valuable insights into the physiological and neurobiological correlates of behavioral coping strategies in response to chronic social stress. Here we aim to identify differences and similarities among stress protocols in mice, with particular attention to how neuroendocrine and/or behavioral responses vary according to different coping strategies, while highlighting the need for standardized approaches in future research. A systematic review was undertaken following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA statement). A total of 213 references were identified by electronic search, and after the screening, 18 articles were found to meet all the established criteria. We analyzed differences in the stress protocol, the characterization and classification of coping strategies and the physiological and behavioral differences according to coping. The results show that differences in behavioural expression under chronic social stress (coping) may also be associated with physiological differences and differential susceptibility to disease. However, this review also underlines the importance of a cautious interpretation of the results obtained. The lack of consistency in the nomenclature and procedures associated with the study of coping strategies for social stress, as well as the absence of a uniform classification, highlight the importance of using a common language when approaching the study of coping strategies. Thereby, this review encourages the development of a more defined method and criteria for assessing coping strategies, based on both behavioral and biological indicators.http://www.sciencedirect.com/science/article/pii/S2352289524000857ChronicSocial stressDefeatCopingBehaviorMice
spellingShingle Alina Díez-Solinska
Zurine De Miguel
Garikoitz Azkona
Oscar Vegas
Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols
Neurobiology of Stress
Chronic
Social stress
Defeat
Coping
Behavior
Mice
title Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols
title_full Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols
title_fullStr Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols
title_full_unstemmed Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols
title_short Behavioral coping with chronic defeat stress in mice: A systematic review of current protocols
title_sort behavioral coping with chronic defeat stress in mice a systematic review of current protocols
topic Chronic
Social stress
Defeat
Coping
Behavior
Mice
url http://www.sciencedirect.com/science/article/pii/S2352289524000857
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AT zurinedemiguel behavioralcopingwithchronicdefeatstressinmiceasystematicreviewofcurrentprotocols
AT garikoitzazkona behavioralcopingwithchronicdefeatstressinmiceasystematicreviewofcurrentprotocols
AT oscarvegas behavioralcopingwithchronicdefeatstressinmiceasystematicreviewofcurrentprotocols