Integrated multi-omics analyses combined with western blotting discovered that cis-TSG alleviated liver injury via modulating lipid metabolism

Integrated multi-omics analyses combined with western blotting discovered that cis-TSG alleviated liver injury via modulating lipid metabolism

Background:Polygonum multiflorum shows dual hepatoprotective and hepatotoxic effects. The bioactive components responsible for these effects are unknown. This study investigates whether cis-2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (cis-TSG), a stilbene glycoside, has hepatoprotective and...

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Bibliographic Details
Main Authors: Tekleab Teka, Jiang Wu, Patrick Kwabena Oduro, Ze Li, Chenxi Wang, Hao Chen, Lin Zhang, Haitao Wang, Liming Wang, Lifeng Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
Subjects:
cis-TSG
stilbene glycoside
cholestasis
metabolomics
lipidomics
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1485035/full
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