Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study
Abstract Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age worldwide, and its related features like obesity, mental health issues and hyperandrogenism may contribute to inadequately investigated health problems such as sexual dysfunction (SD) and...
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-85544-8 |
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| author | Ali Alshiekh Rana Hadakie M Fadi Al Kurdi Luna sukkar Marwan Alhalabi Hamoud Hamed |
| author_facet | Ali Alshiekh Rana Hadakie M Fadi Al Kurdi Luna sukkar Marwan Alhalabi Hamoud Hamed |
| author_sort | Ali Alshiekh |
| collection | DOAJ |
| description | Abstract Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age worldwide, and its related features like obesity, mental health issues and hyperandrogenism may contribute to inadequately investigated health problems such as sexual dysfunction (SD) and lower urinary tract symptoms (LUTS). Therefore, this study examined the impact of PCOS on sexual function (SF) and lower urinary tract in Syrian women by recruiting a total of 178 women of reproductive age, of whom 88 were diagnosed with PCOS according to the Rotterdam criteria and 90 without PCOS were considered as the control group. Female sexual function index (FSFI) and Bristol Female Lower Urinary Tract Symptom Questionnaire (BFLUTS) were used to assess SF and LUTS respectively. PCOS group had higher SD prevalence compared to control group (65.9% vs 48.9%, p = 0.016), and BMI showed an inverse correlation with the total FSFI score in PCOS group (p = 0.027, r = -0.235). Furthermore, PCOS group exhibited significantly lower scores in orgasm and satisfaction subdomains. Additionally, PCOS patients had significantly higher total BFLUTS score compared to control group (median 8 vs 5, p = 0.025). Thus, PCOS may be related to SD and LUTS, highlighting the importance of evaluating SF and urinary symptoms in PCOS patients. |
| format | Article |
| id | doaj-art-38c0efebb77b41c88f60b41a183ee3cb |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-38c0efebb77b41c88f60b41a183ee3cb2025-01-12T12:17:32ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-025-85544-8Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control studyAli Alshiekh0Rana Hadakie1M Fadi Al Kurdi2Luna sukkar3Marwan Alhalabi4Hamoud Hamed5Department of Surgery, Faculty of Medicine, Damascus UniversityDepartment of Biochemistry and Microbiology, Faculty of Pharmacy, Damascus UniversityDepartment of Surgery, Faculty of Medicine, Damascus UniversityDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Damascus UniversityDivision of Reproductive Medicine, Embryology and Genetics, Faculty of Medicine, Damascus UniversityDepartment of Surgery, Faculty of Medicine, Damascus UniversityAbstract Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in women of reproductive age worldwide, and its related features like obesity, mental health issues and hyperandrogenism may contribute to inadequately investigated health problems such as sexual dysfunction (SD) and lower urinary tract symptoms (LUTS). Therefore, this study examined the impact of PCOS on sexual function (SF) and lower urinary tract in Syrian women by recruiting a total of 178 women of reproductive age, of whom 88 were diagnosed with PCOS according to the Rotterdam criteria and 90 without PCOS were considered as the control group. Female sexual function index (FSFI) and Bristol Female Lower Urinary Tract Symptom Questionnaire (BFLUTS) were used to assess SF and LUTS respectively. PCOS group had higher SD prevalence compared to control group (65.9% vs 48.9%, p = 0.016), and BMI showed an inverse correlation with the total FSFI score in PCOS group (p = 0.027, r = -0.235). Furthermore, PCOS group exhibited significantly lower scores in orgasm and satisfaction subdomains. Additionally, PCOS patients had significantly higher total BFLUTS score compared to control group (median 8 vs 5, p = 0.025). Thus, PCOS may be related to SD and LUTS, highlighting the importance of evaluating SF and urinary symptoms in PCOS patients.https://doi.org/10.1038/s41598-025-85544-8PCOSSexual dysfunctionLower urinary tract symptomsFSFIBFLUTS |
| spellingShingle | Ali Alshiekh Rana Hadakie M Fadi Al Kurdi Luna sukkar Marwan Alhalabi Hamoud Hamed Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study Scientific Reports PCOS Sexual dysfunction Lower urinary tract symptoms FSFI BFLUTS |
| title | Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study |
| title_full | Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study |
| title_fullStr | Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study |
| title_full_unstemmed | Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study |
| title_short | Polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women: a case-control study |
| title_sort | polycystic ovary syndrome negatively affects sexual function and lower urinary tract symptoms in syrian women a case control study |
| topic | PCOS Sexual dysfunction Lower urinary tract symptoms FSFI BFLUTS |
| url | https://doi.org/10.1038/s41598-025-85544-8 |
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