GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand

GFRα1 Promotes Axon Regeneration after Peripheral Nerve Injury by Functioning as a Ligand

Abstract The neurotrophic factor, Glial cell line derived neurotrophi factor (GDNF), exerts a variety of biological effects through binding to its receptors, GDNF family receptor alpha‐1 (GFRα1), and RET. However, the existence of cells expressing GFRα1 but not RET raises the possibility that GFRα1...

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Bibliographic Details
Main Authors: Tomoaki Suzuki, Ken Kadoya, Takeshi Endo, Miwako Yamasaki, Masahiko Watanabe, Norimasa Iwasaki
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
axon regeneration
GDNF family receptor
peripheral nerve injury
repair schwann cells
Online Access:https://doi.org/10.1002/advs.202400812
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