Y665F variant of mouse Stat5b protects against acute kidney injury through transcriptomic shifts in renal gene expression
Abstract The impact of single nucleotide polymorphisms (SNP) on physiology is often underestimated. One amino acid change can result in a variety of phenotypes apparent only in response to disease or injury. Even known pathogenic SNPs have widespread effects that are currently unaccounted for. In th...
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| Main Authors: | Jakub Jankowski, Hye Kyung Lee, Lothar Hennighausen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-15812-0 |
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