Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice

Resveratrol promotes cholesterol efflux from dendritic cells and controls costimulation and T-cell activation in high-fat and lipopolysaccharide-driven atherosclerotic mice

Cholesterol aggregation in dendritic cells (DCs) triggers an inflammatory response and accelerates the development of atherosclerosis (AS). Resveratrol (RES), a natural compound with anti-inflammatory and cholesterol metabolism regulatory properties, has been shown to influence the maturation and in...

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Bibliographic Details
Main Authors: Linhui Zhang, Haixia Wang, Zishan Wang, Jianyi Xu, Mengyuan Wang, Wenxin Wang, Qiongshan He, Yun Yu, Dongping Yuan, Guirong Bu, Runze Qiu, Jun Long
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atherosclerosis
resveratrol
dendritic cells
T cells
cholesterol efflux
ABCA1
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1450898/full
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