Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates
In this study, we present a straightforward, resource-efficient, and environmentally sustainable approach for the synthesis of α-hydroxyphosphonate derivatives. This synthetic methodology involves the reaction of aromatic aldehydes with triethylphosphite and utilizes microwave irradiation as a sourc...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Chemistry Proceedings |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-4583/14/1/91 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846105268820115456 |
|---|---|
| author | Abdeslem Bouzina Yousra Ouafa Bouone Rachida Mansouri Nour-Eddine Aouf |
| author_facet | Abdeslem Bouzina Yousra Ouafa Bouone Rachida Mansouri Nour-Eddine Aouf |
| author_sort | Abdeslem Bouzina |
| collection | DOAJ |
| description | In this study, we present a straightforward, resource-efficient, and environmentally sustainable approach for the synthesis of α-hydroxyphosphonate derivatives. This synthetic methodology involves the reaction of aromatic aldehydes with triethylphosphite and utilizes microwave irradiation as a source of activation energy and was catalyzed by bismuth chloride III at an amount of 20 mol%. The protocol affords rapid and highly efficient results, yielding α-hydroxyphosphonates in high yields while minimizing reaction times. |
| format | Article |
| id | doaj-art-37aa6592e776461b97d3c83d62b06f46 |
| institution | Kabale University |
| issn | 2673-4583 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemistry Proceedings |
| spelling | doaj-art-37aa6592e776461b97d3c83d62b06f462024-12-27T14:17:33ZengMDPI AGChemistry Proceedings2673-45832023-11-011419110.3390/ecsoc-27-16282Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-HydroxyphosphonatesAbdeslem Bouzina0Yousra Ouafa Bouone1Rachida Mansouri2Nour-Eddine Aouf3Laboratory of Applied Organic Chemistry, Bioorganic Chemistry Group, Department of Chemistry, Sciences Faculty, Badji Mokhtar Annaba University, Box 12, Annaba 23000, AlgeriaLaboratory of Applied Organic Chemistry, Bioorganic Chemistry Group, Department of Chemistry, Sciences Faculty, Badji Mokhtar Annaba University, Box 12, Annaba 23000, AlgeriaEnvironmental Research Center (CRE), Annaba 23000, AlgeriaLaboratory of Applied Organic Chemistry, Bioorganic Chemistry Group, Department of Chemistry, Sciences Faculty, Badji Mokhtar Annaba University, Box 12, Annaba 23000, AlgeriaIn this study, we present a straightforward, resource-efficient, and environmentally sustainable approach for the synthesis of α-hydroxyphosphonate derivatives. This synthetic methodology involves the reaction of aromatic aldehydes with triethylphosphite and utilizes microwave irradiation as a source of activation energy and was catalyzed by bismuth chloride III at an amount of 20 mol%. The protocol affords rapid and highly efficient results, yielding α-hydroxyphosphonates in high yields while minimizing reaction times.https://www.mdpi.com/2673-4583/14/1/91α-hydroxyphosphonatesmicrowave irradiationcatalyst freegreen synthesissolvent free |
| spellingShingle | Abdeslem Bouzina Yousra Ouafa Bouone Rachida Mansouri Nour-Eddine Aouf Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates Chemistry Proceedings α-hydroxyphosphonates microwave irradiation catalyst free green synthesis solvent free |
| title | Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates |
| title_full | Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates |
| title_fullStr | Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates |
| title_full_unstemmed | Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates |
| title_short | Microwave-Assisted BiCl<sub>3</sub> Catalyzed Synthesis of α-Hydroxyphosphonates |
| title_sort | microwave assisted bicl sub 3 sub catalyzed synthesis of α hydroxyphosphonates |
| topic | α-hydroxyphosphonates microwave irradiation catalyst free green synthesis solvent free |
| url | https://www.mdpi.com/2673-4583/14/1/91 |
| work_keys_str_mv | AT abdeslembouzina microwaveassistedbiclsub3subcatalyzedsynthesisofahydroxyphosphonates AT yousraouafabouone microwaveassistedbiclsub3subcatalyzedsynthesisofahydroxyphosphonates AT rachidamansouri microwaveassistedbiclsub3subcatalyzedsynthesisofahydroxyphosphonates AT noureddineaouf microwaveassistedbiclsub3subcatalyzedsynthesisofahydroxyphosphonates |