Promotion of mandibular distraction osteogenesis by parathyroid hormone via macrophage polarization induced through iNOS downregulation

Promotion of mandibular distraction osteogenesis by parathyroid hormone via macrophage polarization induced through iNOS downregulation

Objective: To investigate whether Parathyroid hormone (PTH) can promote mandibular distraction osteogenesis by regulating macrophage polarization and the underlying mechanisms of this phenomenon. Methods: Forty-eight Rabbits were used to establish the mandibular distraction osteogenesis experimental...

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Bibliographic Details
Main Authors: Dong-xiang Wang, Zhi-shan Yang, Du-chenhui Li, Yong-di Li, Yu Wang, You-li Chen, Zheng-long Tang
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Macrophage
Distraction osteogenesis
Parathyroid hormone
Mandible
Inducible nitric oxide synthase
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024145951
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