L-Methioninase as a Selective Anticancer Agent: Dose-Dependent Cytotoxicity and Metastasis Suppression in Methionine-Dependent Tumor Cells

L-Methioninase as a Selective Anticancer Agent: Dose-Dependent Cytotoxicity and Metastasis Suppression in Methionine-Dependent Tumor Cells

L-methioninase (L-Met), a methionine-degrading enzyme, has shown potential for anticancer therapy. Many tumor tissues have a limited ability to produce methionine and depend on external sources; hence, these tumors can be targeted by methionine-based treatments. The present study was conducted to i...

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Bibliographic Details
Main Authors: Abbas Abed Noor Al-Owaidi, Mohammed Abdullah Jebor
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-07-01
Series:Acta Medica Iranica
Subjects:
L-methioninase
Pseudomonas aeruginosa
Hepatocellular carcinoma
Pancreatic carcinoma
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/11460
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