Impact of early initiation of renal replacement therapy in patients on venoarterial ECMO using target trial emulation with Japanese nationwide data

Impact of early initiation of renal replacement therapy in patients on venoarterial ECMO using target trial emulation with Japanese nationwide data

Abstract While renal replacement therapy (RRT) allows for precise fluid management as well as addressing electrolyte imbalances and the removal of other necessary compounds, its early initiation has not shown benefit in the general critically ill population. Moreover, the effects of early RRT initia...

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Main Authors: Toshihiro Kubo, Tomonori Takeuchi, Norihiko Inoue, Augusto Cama-Olivares, Deepak Chandramohan, Ashita J. Tolwani, Keith M. Wille, Kiyohide Fushimi, Javier A. Neyra, Kenji Wakabayashi
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Venoarterial extracorporeal membrane oxygenation
Renal replacement therapy
Target trial emulation
Online Access:https://doi.org/10.1038/s41598-025-85109-9
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