Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study
Abstract Background Higher consumption of sugary beverages (SB) has been associated with type 2 diabetes (T2D), but whether these associations are modified by physical activity remains unclear. This study aimed to examine the associations of SB intake, including sugar-sweetened beverages (SSB), arti...
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| Format: | Article |
| Language: | English |
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2024-11-01
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| Series: | Nutrition Journal |
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| Online Access: | https://doi.org/10.1186/s12937-024-01006-3 |
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| author | Yihong Ding Hui Chen Jie Shen Liyan Huang Yaying Cao Yan Zheng Geng Zong Changzheng Yuan |
| author_facet | Yihong Ding Hui Chen Jie Shen Liyan Huang Yaying Cao Yan Zheng Geng Zong Changzheng Yuan |
| author_sort | Yihong Ding |
| collection | DOAJ |
| description | Abstract Background Higher consumption of sugary beverages (SB) has been associated with type 2 diabetes (T2D), but whether these associations are modified by physical activity remains unclear. This study aimed to examine the associations of SB intake, including sugar-sweetened beverages (SSB), artificially sweetened beverages (ASB), and natural juices (NJ) with the risk of incident T2D, and the potential role of physical activity. Methods We included 153,862 diabetes-free participants in the UK Biobank who completed both the International Physical Activity Questionnaire at recruitment (2006–2010) and at least one 24-h dietary recall questionnaire in 2009–2012. We assessed the associations of each SB with the risk of incident T2D using Cox proportional hazard models, and explored the interactions between each SB and physical activity. Results During a median follow-up of 11.8 years, 6631 participants developed incident T2D. Participants consuming more SSB and ASB (comparing > 2 to 0 unit/d) had a higher hazard of T2D (hazard ratio [HR]: 1.17, 95% confidence interval [CI]: 1.05–1.31 for SSB; 1.54, 1.37–1.74 for ASB), while medium intake of NJ showed an inverse association (HR> 0–1 vs. 0 unit/d: 0.87, 95% CI: 0.82–0.92; HR> 1–2 vs. 0 unit/d: 0.88, 95% CI: 0.81–0.97) with incident T2D. No significant interactions between physical activity and SSB/ASB were found (P-interaction=0.204 for SSB, 0.926 for ASB), but the protective association of medium NJ intake with T2D was stronger among participants with higher level of physical activity (P-interaction = 0.043). Conclusions Higher intake of SSB and ASB was related to higher risks of T2D. Medium NJ intake was associated with a lower risk of T2D, particularly among individuals with higher physical activity level. These findings emphasized the importance of healthy beverage intake and adequate physical activity in diabetes prevention. |
| format | Article |
| id | doaj-art-36f2088c75634908ba5dfd4d34a1054a |
| institution | Kabale University |
| issn | 1475-2891 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition Journal |
| spelling | doaj-art-36f2088c75634908ba5dfd4d34a1054a2024-11-10T12:08:58ZengBMCNutrition Journal1475-28912024-11-0123111010.1186/s12937-024-01006-3Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort studyYihong Ding0Hui Chen1Jie Shen2Liyan Huang3Yaying Cao4Yan Zheng5Geng Zong6Changzheng Yuan7School of Public Health, the Second Affiliated Hospital, Zhejiang University School of MedicineSchool of Public Health, the Second Affiliated Hospital, Zhejiang University School of MedicineSchool of Public Health, the Second Affiliated Hospital, Zhejiang University School of MedicineSchool of Public Health, the Second Affiliated Hospital, Zhejiang University School of MedicineCAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of SciencesState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan UniversityCAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of SciencesSchool of Public Health, the Second Affiliated Hospital, Zhejiang University School of MedicineAbstract Background Higher consumption of sugary beverages (SB) has been associated with type 2 diabetes (T2D), but whether these associations are modified by physical activity remains unclear. This study aimed to examine the associations of SB intake, including sugar-sweetened beverages (SSB), artificially sweetened beverages (ASB), and natural juices (NJ) with the risk of incident T2D, and the potential role of physical activity. Methods We included 153,862 diabetes-free participants in the UK Biobank who completed both the International Physical Activity Questionnaire at recruitment (2006–2010) and at least one 24-h dietary recall questionnaire in 2009–2012. We assessed the associations of each SB with the risk of incident T2D using Cox proportional hazard models, and explored the interactions between each SB and physical activity. Results During a median follow-up of 11.8 years, 6631 participants developed incident T2D. Participants consuming more SSB and ASB (comparing > 2 to 0 unit/d) had a higher hazard of T2D (hazard ratio [HR]: 1.17, 95% confidence interval [CI]: 1.05–1.31 for SSB; 1.54, 1.37–1.74 for ASB), while medium intake of NJ showed an inverse association (HR> 0–1 vs. 0 unit/d: 0.87, 95% CI: 0.82–0.92; HR> 1–2 vs. 0 unit/d: 0.88, 95% CI: 0.81–0.97) with incident T2D. No significant interactions between physical activity and SSB/ASB were found (P-interaction=0.204 for SSB, 0.926 for ASB), but the protective association of medium NJ intake with T2D was stronger among participants with higher level of physical activity (P-interaction = 0.043). Conclusions Higher intake of SSB and ASB was related to higher risks of T2D. Medium NJ intake was associated with a lower risk of T2D, particularly among individuals with higher physical activity level. These findings emphasized the importance of healthy beverage intake and adequate physical activity in diabetes prevention.https://doi.org/10.1186/s12937-024-01006-3Sugary beveragesPhysical activityType 2 diabetesInteractionsCohort study |
| spellingShingle | Yihong Ding Hui Chen Jie Shen Liyan Huang Yaying Cao Yan Zheng Geng Zong Changzheng Yuan Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study Nutrition Journal Sugary beverages Physical activity Type 2 diabetes Interactions Cohort study |
| title | Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study |
| title_full | Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study |
| title_fullStr | Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study |
| title_full_unstemmed | Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study |
| title_short | Associations of sugary beverage intake with type 2 diabetes and the role of physical activity: a prospective cohort study |
| title_sort | associations of sugary beverage intake with type 2 diabetes and the role of physical activity a prospective cohort study |
| topic | Sugary beverages Physical activity Type 2 diabetes Interactions Cohort study |
| url | https://doi.org/10.1186/s12937-024-01006-3 |
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