The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur

Pityriasis versicolor is one of the most common fungal infections on the skin caused by Malassezia furfur. Kaffir lime fruit (Citrus hystrix DC), especially its peels’ contents in secondary metabolite, may play a healing role against such infections. Therefore, the aim of this study was to determine...

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Main Authors: Mulyati Sri Rahayu, Nailah Najah, Wizar Putri Mellaratna
Format: Article
Language:English
Published: International Journal of Secondary Metabolite 2024-08-01
Series:International Journal of Secondary Metabolite
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Online Access:https://dergipark.org.tr/en/download/article-file/3557755
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author Mulyati Sri Rahayu
Nailah Najah
Wizar Putri Mellaratna
author_facet Mulyati Sri Rahayu
Nailah Najah
Wizar Putri Mellaratna
author_sort Mulyati Sri Rahayu
collection DOAJ
description Pityriasis versicolor is one of the most common fungal infections on the skin caused by Malassezia furfur. Kaffir lime fruit (Citrus hystrix DC), especially its peels’ contents in secondary metabolite, may play a healing role against such infections. Therefore, the aim of this study was to determine the antifungal potential of Kaffir lime peel extract against Malassezia furfur. Ethanol extracts of the peels of Kaffir lime were tested for its antifungal properties against Malassezia furfur at different tested concentrations, namely 25%, 50%, 75%, and 100%. Every treatment was performed with 4 replications. Inhibition zone formed surrounding the paper disc measured after 24 hours of incubation using the caliper method. Data were subjected to the Kruskal-Wallis test and the Mann-Whitney Post hoc test. The study revealed that the kaffir lime fruit extract gave a significant effect on the inhibition zone (p< 0.05). The results showed that the higher inhibition zone was found at control group and it was different significantly from other treatments. However, among the tested concentrations, the best treatment was detected at a concentration of 100%, which was significantly different from other concentrations. Kaffir lime peel has an antifungal effect against Malassezia furfur and the best tested concentration was 100%.
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spelling doaj-art-36d36532eeed4a19b7a14c9d1ce335892024-12-06T11:03:54ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052024-08-0111348649310.21448/ijsm.1395562618The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfurMulyati Sri Rahayu0https://orcid.org/0000-0001-7480-2485Nailah Najah1https://orcid.org/0009-0001-6286-8687Wizar Putri Mellaratna2https://orcid.org/0000-0002-5945-8898Universitas Malikussalehuniversitas malikussalehUniversitas Malikussaleh,Pityriasis versicolor is one of the most common fungal infections on the skin caused by Malassezia furfur. Kaffir lime fruit (Citrus hystrix DC), especially its peels’ contents in secondary metabolite, may play a healing role against such infections. Therefore, the aim of this study was to determine the antifungal potential of Kaffir lime peel extract against Malassezia furfur. Ethanol extracts of the peels of Kaffir lime were tested for its antifungal properties against Malassezia furfur at different tested concentrations, namely 25%, 50%, 75%, and 100%. Every treatment was performed with 4 replications. Inhibition zone formed surrounding the paper disc measured after 24 hours of incubation using the caliper method. Data were subjected to the Kruskal-Wallis test and the Mann-Whitney Post hoc test. The study revealed that the kaffir lime fruit extract gave a significant effect on the inhibition zone (p< 0.05). The results showed that the higher inhibition zone was found at control group and it was different significantly from other treatments. However, among the tested concentrations, the best treatment was detected at a concentration of 100%, which was significantly different from other concentrations. Kaffir lime peel has an antifungal effect against Malassezia furfur and the best tested concentration was 100%.https://dergipark.org.tr/en/download/article-file/3557755antifungal inhibition zonekaffir lime peelsmalassezia furfurantifungal inhibition zonekaffir lime peelsmalassezia furfur
spellingShingle Mulyati Sri Rahayu
Nailah Najah
Wizar Putri Mellaratna
The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur
International Journal of Secondary Metabolite
antifungal inhibition zone
kaffir lime peels
malassezia furfur
antifungal inhibition zone
kaffir lime peels
malassezia furfur
title The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur
title_full The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur
title_fullStr The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur
title_full_unstemmed The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur
title_short The preliminary study on the antifungal effect of Kaffir lime (Citrus hystrix DC) peel extract against Malassezia furfur
title_sort preliminary study on the antifungal effect of kaffir lime citrus hystrix dc peel extract against malassezia furfur
topic antifungal inhibition zone
kaffir lime peels
malassezia furfur
antifungal inhibition zone
kaffir lime peels
malassezia furfur
url https://dergipark.org.tr/en/download/article-file/3557755
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