Carcinoembryonic antigen trajectory predicts pathological complete response in advanced gastric cancer after neoadjuvant chemotherapy

Carcinoembryonic antigen trajectory predicts pathological complete response in advanced gastric cancer after neoadjuvant chemotherapy

AimsThis study aims to develop a simple, clinically applicable classification system to predict pCR based on carcinoembryonic antigen (CEA) trajectory during NAC.MethodsThis study included 366 AGC patients who received NAC followed by radical gastrectomy. CEA levels were measured before, during, and...

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Bibliographic Details
Main Authors: Yonghe Chen, Dan Liu, Kaikai Wei, Yi Lin, Zhong Wang, Qian Sun, Huashe Wang, Junsheng Peng, Lei Lian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
carcinoembryonic antigen
trajectory analysis (TA)
pathological complete response
neoadjuvant chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1525324/full
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