Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma
Abstract Follicular dendritic cell sarcoma (FDCS) is a rare malignancy, often challenging to diagnose due to its nonspecific presentation and resemblance to other neoplasms. This case highlights a locally advanced nasopharyngeal FDCS initially misdiagnosed as a meningioma, underscoring the importanc...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Springer
2025-01-01
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| Series: | Discover Oncology |
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| Online Access: | https://doi.org/10.1007/s12672-024-01366-6 |
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| author | Yoldez Houcine Abir Rais Salma Kamoun Sawssen Dhambri Souhaeil Jebali Maha Driss |
| author_facet | Yoldez Houcine Abir Rais Salma Kamoun Sawssen Dhambri Souhaeil Jebali Maha Driss |
| author_sort | Yoldez Houcine |
| collection | DOAJ |
| description | Abstract Follicular dendritic cell sarcoma (FDCS) is a rare malignancy, often challenging to diagnose due to its nonspecific presentation and resemblance to other neoplasms. This case highlights a locally advanced nasopharyngeal FDCS initially misdiagnosed as a meningioma, underscoring the importance of differential diagnosis in unusual tumor presentations. A 77-year-old patient presented with nasal obstruction for 3 months. Imaging studies revealed a mass in the nasopharynx prolapsing into the oropharynx, leading to an initial diagnosis of meningioma based on its radiologic appearance. Surgical resection was performed, and histopathological examination, supplemented by immunohistochmical staining, revealed features consistent with follicular dendritic cell sarcoma. The tumor was locally advanced, involving surrounding structures, which complicated the initial clinical and radiologic assessment. |
| format | Article |
| id | doaj-art-36b5b330440043ea8e56f0202326f0f5 |
| institution | Kabale University |
| issn | 2730-6011 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Oncology |
| spelling | doaj-art-36b5b330440043ea8e56f0202326f0f52025-01-12T12:29:16ZengSpringerDiscover Oncology2730-60112025-01-011611610.1007/s12672-024-01366-6Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningiomaYoldez Houcine0Abir Rais1Salma Kamoun2Sawssen Dhambri3Souhaeil Jebali4Maha Driss5Pathology Department, Salah Azeiz InstitutePathology Department, Salah Azeiz InstitutePathology Department, Salah Azeiz InstituteOto-Rhino-Laryngology and maxillo-facial surgery Department, Salah Azeiz InstituteOto-Rhino-Laryngology and maxillo-facial surgery Department, Salah Azeiz InstitutePathology Department, Salah Azeiz InstituteAbstract Follicular dendritic cell sarcoma (FDCS) is a rare malignancy, often challenging to diagnose due to its nonspecific presentation and resemblance to other neoplasms. This case highlights a locally advanced nasopharyngeal FDCS initially misdiagnosed as a meningioma, underscoring the importance of differential diagnosis in unusual tumor presentations. A 77-year-old patient presented with nasal obstruction for 3 months. Imaging studies revealed a mass in the nasopharynx prolapsing into the oropharynx, leading to an initial diagnosis of meningioma based on its radiologic appearance. Surgical resection was performed, and histopathological examination, supplemented by immunohistochmical staining, revealed features consistent with follicular dendritic cell sarcoma. The tumor was locally advanced, involving surrounding structures, which complicated the initial clinical and radiologic assessment.https://doi.org/10.1007/s12672-024-01366-6Follicular dendritic cell sarcomaNasopharynxDifferential diagnosesImmunphistochemistry |
| spellingShingle | Yoldez Houcine Abir Rais Salma Kamoun Sawssen Dhambri Souhaeil Jebali Maha Driss Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma Discover Oncology Follicular dendritic cell sarcoma Nasopharynx Differential diagnoses Immunphistochemistry |
| title | Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma |
| title_full | Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma |
| title_fullStr | Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma |
| title_full_unstemmed | Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma |
| title_short | Locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma |
| title_sort | locally advanced nasopharyngeal follicular dendritic cell sarcoma misdiagnosed as meningioma |
| topic | Follicular dendritic cell sarcoma Nasopharynx Differential diagnoses Immunphistochemistry |
| url | https://doi.org/10.1007/s12672-024-01366-6 |
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