Reduced Insulin-like Growth Factor Levels in Pre-Menopausal Women with Endometrial Cancer

Reduced Insulin-like Growth Factor Levels in Pre-Menopausal Women with Endometrial Cancer

The rising global incidence of uterine cancer has been linked to the escalating prevalence of obesity. Obesity results in insulin resistance which alters the IGF system, thereby driving cancer progression via increased cell proliferation and the inhibition of apoptosis, although the precise mechanis...

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Bibliographic Details
Main Authors: Irene Ray, Carla S. Möller-Levet, Agnieszka Michael, Lisiane B. Meira, Patricia E. Ellis
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Journal of Molecular Pathology
Subjects:
insulin-like growth factor
IGF
endometrial cancer risk
obesity
menopause
ROC curve
Online Access:https://www.mdpi.com/2673-5261/5/4/31
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