Single-Cell Spatial–Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8+ T Cell Dysfunction

Single-Cell Spatial–Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8+ T Cell Dysfunction

Cisplatin is widely used to treat osteosarcoma, but recurrent cases often develop resistance, allowing the disease to progress and complicating clinical management. This study aimed to elucidate the immune microenvironment of osteosarcoma, providing insights into the mechanisms of recurrence and ide...

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Main Authors: Ning Tang, Woding Deng, Yupeng Wu, Zhixuan Deng, Xin Wu, Jianbin Xiong, Qiangqiang Zhao
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2024-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0530
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