Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src

Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src

Abstract Background The treatment options to delay the progression of diabetic nephropathy (DN), a key contributor to chronic kidney disease (CKD), are urgently needed. Previous studies reported that traditional Chinese medicine Panax notoginseng (PNG) exerted beneficial effects on DN. However, the...

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Bibliographic Details
Main Authors: Xieyi Guo, Liu Yang, Xiaoning An, Maofang Hu, Yilan Shen, Niansong Wang, Youhua Xu, Dingkun Gui
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Chinese Medicine
Subjects:
Notoginsenoside R2
Diabetic nephropathy
c-Src
Lipid accumulation
Mitochondrial dysfunction
Online Access:https://doi.org/10.1186/s13020-024-01057-y
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