Interference of Interleukin-1β Mediated by Lentivirus Promotes Functional Recovery of Spinal Cord Contusion Injury in Rats via the PI3K/AKT1 Signaling Pathway

Purpose. Inflammation and apoptosis after spinal cord contusion (SCC) are important causes of irreversible spinal cord injury. Interleukin-1β (IL-1β) is a key inflammatory factor that promotes the aggravation of spinal cord contusion. However, the specific role and regulatory mechanism of IL-1β in s...

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Main Authors: Jun-Feng Cao, Xi Hu, Li Xiong, Mei Wu, Xingyu Yang, Chaochao Wang, Shengyan Chen, Hengxiang Xu, Huanyu Chen, Xuntai Ma, Yongjie Mi, Xiao Zhang
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2022/6285099
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