The effects of aerobic exercise and heat stress on the unbound fraction of caffeine
IntroductionThe fraction of drug circulating in the blood that is not bound to plasma proteins (fu) is considered pharmacologically active since it readily binds to its receptor. In vitro evidence suggests that changes in temperature and pH affect the affinity of drug binding to plasma proteins, res...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2024.1370586/full |
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