Hydrochlorothiazide disrupts DNA damage response to exacerbate skin photosensitivity

Hydrochlorothiazide (HCTZ) is a widely utilized diuretic for the treatment of hypertension. The photosensitivity of HCTZ has been recognized for six decades, with UVA being considered the primary culprit. However, the precise molecular mechanism of HCTZ sensitizing skin to UV radiation remains unkno...

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Bibliographic Details
Main Authors: Lei Tao, Yujiao Xu, Yingyue Cui, Qingcheng Wei, Boyang Lin, Yu Cao, Zhen Dai, Zhi Ma, Ling Zhang, Aiping Shi, Ling Gu, Yunyao Liu
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324013903
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