Kounis syndrome following moxifloxacin and deflazacort administration
Kounis syndrome (KS), characterized by the simultaneous occurrence of acute coronary syndrome (ACS) and allergic reactions, can be triggered by a range of factors and drugs. We report on the case of a patient who arrived at our emergency department (ED) with symptoms of an allergic reaction after ta...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2024-12-01
|
| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/4971 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841556079315517440 |
|---|---|
| author | Eugenia Morello Silvia Bosio Sibilla Anna Teresa Salvadeo |
| author_facet | Eugenia Morello Silvia Bosio Sibilla Anna Teresa Salvadeo |
| author_sort | Eugenia Morello |
| collection | DOAJ |
| description | Kounis syndrome (KS), characterized by the simultaneous occurrence of acute coronary syndrome (ACS) and allergic reactions, can be triggered by a range of factors and drugs. We report on the case of a patient who arrived at our emergency department (ED) with symptoms of an allergic reaction after taking moxifloxacin and deflazacort orally. In the ED, the patient experienced a 5-minute episode of oppressive chest pain. A 12-lead electrocardiogram (ECG) was registered, and elevated troponin levels were detected in the blood, suggesting myocardial damage. The patient was admitted to the internal medicine department for observation, and a second 12-lead ECG demonstrated a significant variation in the repolarization pattern. The day after, a coronary angiography revealed no significant stenosis, thus supporting, along with elevated serum tryptase levels, the diagnosis of KS. This case report highlights two potential triggers for KS and emphasizes the critical importance of early recognition and prompt treatment of KS. |
| format | Article |
| id | doaj-art-355a2b3f16184cb7baa1a8b28c106b81 |
| institution | Kabale University |
| issn | 2284-2594 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj-art-355a2b3f16184cb7baa1a8b28c106b812025-01-07T13:40:28ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942024-12-0110.12890/2024_0049714506Kounis syndrome following moxifloxacin and deflazacort administrationEugenia Morello0Silvia Bosio1Sibilla Anna Teresa Salvadeo2Emergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Bellinzona e Valli, Bellinzona, SwitzerlandEmergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Lugano, Lugano, SwitzerlandEmergency Department, Ente Ospedaliero Cantonale - Ospedale Regionale di Lugano, Lugano, SwitzerlandKounis syndrome (KS), characterized by the simultaneous occurrence of acute coronary syndrome (ACS) and allergic reactions, can be triggered by a range of factors and drugs. We report on the case of a patient who arrived at our emergency department (ED) with symptoms of an allergic reaction after taking moxifloxacin and deflazacort orally. In the ED, the patient experienced a 5-minute episode of oppressive chest pain. A 12-lead electrocardiogram (ECG) was registered, and elevated troponin levels were detected in the blood, suggesting myocardial damage. The patient was admitted to the internal medicine department for observation, and a second 12-lead ECG demonstrated a significant variation in the repolarization pattern. The day after, a coronary angiography revealed no significant stenosis, thus supporting, along with elevated serum tryptase levels, the diagnosis of KS. This case report highlights two potential triggers for KS and emphasizes the critical importance of early recognition and prompt treatment of KS.https://www.ejcrim.com/index.php/EJCRIM/article/view/4971kounis syndromeallergic reactioncoronary disease |
| spellingShingle | Eugenia Morello Silvia Bosio Sibilla Anna Teresa Salvadeo Kounis syndrome following moxifloxacin and deflazacort administration European Journal of Case Reports in Internal Medicine kounis syndrome allergic reaction coronary disease |
| title | Kounis syndrome following moxifloxacin and deflazacort administration |
| title_full | Kounis syndrome following moxifloxacin and deflazacort administration |
| title_fullStr | Kounis syndrome following moxifloxacin and deflazacort administration |
| title_full_unstemmed | Kounis syndrome following moxifloxacin and deflazacort administration |
| title_short | Kounis syndrome following moxifloxacin and deflazacort administration |
| title_sort | kounis syndrome following moxifloxacin and deflazacort administration |
| topic | kounis syndrome allergic reaction coronary disease |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/4971 |
| work_keys_str_mv | AT eugeniamorello kounissyndromefollowingmoxifloxacinanddeflazacortadministration AT silviabosio kounissyndromefollowingmoxifloxacinanddeflazacortadministration AT sibillaannateresasalvadeo kounissyndromefollowingmoxifloxacinanddeflazacortadministration |