Heat application in live cell imaging

Thermal heating of biological samples allows to reversibly manipulate cellular processes with high temporal and spatial resolution. Manifold heating techniques in combination with live‐cell imaging were developed, commonly tailored to customized applications. They include Peltier elements and microf...

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Main Authors: Linda Sistemich, Simon Ebbinghaus
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13912
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author Linda Sistemich
Simon Ebbinghaus
author_facet Linda Sistemich
Simon Ebbinghaus
author_sort Linda Sistemich
collection DOAJ
description Thermal heating of biological samples allows to reversibly manipulate cellular processes with high temporal and spatial resolution. Manifold heating techniques in combination with live‐cell imaging were developed, commonly tailored to customized applications. They include Peltier elements and microfluidics for homogenous sample heating as well as infrared lasers and radiation absorption by nanostructures for spot heating. A prerequisite of all techniques is that the induced temperature changes are measured precisely which can be the main challenge considering subcellular structures or multicellular organisms as target regions. This article discusses heating and temperature sensing techniques for live‐cell imaging, leading to future applications in cell biology.
format Article
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institution Kabale University
issn 2211-5463
language English
publishDate 2024-12-01
publisher Wiley
record_format Article
series FEBS Open Bio
spelling doaj-art-350735dc18764ad192e1436815f0f33d2024-12-02T09:49:10ZengWileyFEBS Open Bio2211-54632024-12-0114121940195410.1002/2211-5463.13912Heat application in live cell imagingLinda Sistemich0Simon Ebbinghaus1Chair of Biophysical Chemistry Ruhr‐University Bochum GermanyChair of Biophysical Chemistry Ruhr‐University Bochum GermanyThermal heating of biological samples allows to reversibly manipulate cellular processes with high temporal and spatial resolution. Manifold heating techniques in combination with live‐cell imaging were developed, commonly tailored to customized applications. They include Peltier elements and microfluidics for homogenous sample heating as well as infrared lasers and radiation absorption by nanostructures for spot heating. A prerequisite of all techniques is that the induced temperature changes are measured precisely which can be the main challenge considering subcellular structures or multicellular organisms as target regions. This article discusses heating and temperature sensing techniques for live‐cell imaging, leading to future applications in cell biology.https://doi.org/10.1002/2211-5463.13912fluorescence microscopylive‐cell imagingmicroheatingthermometry
spellingShingle Linda Sistemich
Simon Ebbinghaus
Heat application in live cell imaging
FEBS Open Bio
fluorescence microscopy
live‐cell imaging
microheating
thermometry
title Heat application in live cell imaging
title_full Heat application in live cell imaging
title_fullStr Heat application in live cell imaging
title_full_unstemmed Heat application in live cell imaging
title_short Heat application in live cell imaging
title_sort heat application in live cell imaging
topic fluorescence microscopy
live‐cell imaging
microheating
thermometry
url https://doi.org/10.1002/2211-5463.13912
work_keys_str_mv AT lindasistemich heatapplicationinlivecellimaging
AT simonebbinghaus heatapplicationinlivecellimaging