Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology
ABSTRACT Background Primary gastrointestinal (GI) follicular lymphoma (FL) is a rare entity, and colorectal FL presenting as a solitary polyp is particularly uncommon. Case Presentation A 60‐year‐old woman presented with hematochezia. Colonoscopy incidentally identified an 8‐mm polyp in the transver...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-05-01
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| Series: | JGH Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jgh3.70170 |
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| Summary: | ABSTRACT Background Primary gastrointestinal (GI) follicular lymphoma (FL) is a rare entity, and colorectal FL presenting as a solitary polyp is particularly uncommon. Case Presentation A 60‐year‐old woman presented with hematochezia. Colonoscopy incidentally identified an 8‐mm polyp in the transverse colon, which was subsequently removed via cold snare polypectomy. Histopathological examination confirmed Grade 1 FL, with immunohistochemical analysis revealing positivity for CD10, CD20, and Bcl‐2. Further diagnostic evaluation demonstrated FL involvement in the proximal jejunum, leading to a diagnosis of clinical stage I primary GI‐FL. The patient elected to undergo a watch‐and‐wait approach. Conclusion This case highlights the potential for colorectal‐FL lesions to be misidentified as adenomatous polyps, posing a diagnostic challenge. |
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| ISSN: | 2397-9070 |