New pneumococcal serotype 20C is a WciG O-acetyltransferase deficient variant of canonical serotype 20B
ABSTRACT The polysaccharide (PS) capsule of Streptococcus pneumoniae (pneumococcus) is the immunodominant surface structure that shields the bacteria from the host immune system. Since the capsule is the primary target of currently available pneumococcal vaccines, anti-capsular antibodies are highly...
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Main Authors: | Jigui Yu, Neil Ravenscroft, Peter Davey, Roshan Liyanage, Oliver Lorenz, Michelle M. Kuttel, Stephanie W. Lo, Feroze A. Ganaie, Moon H. Nahm |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2025-01-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.02443-24 |
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