Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress

Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress

Cells react to stress by triggering response pathways, leading to extensive alterations in the transcriptome to restore cellular homeostasis. The role of RNA metabolism in shaping the cellular response to stress is vital, yet the global changes in RNA stability under these conditions remain unclear....

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Bibliographic Details
Main Authors: Showkat Ahmad Dar, Sulochan Malla, Vlastimil Martinek, Matthew John Payea, Christopher Tai-Yi Lee, Jessica Martin, Aditya Jignesh Khandeshi, Jennifer L Martindale, Cedric Belair, Manolis Maragkakis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
stress response
cell line
RNA decay
Online Access:https://elifesciences.org/articles/96284
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