Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies

Targeting protein homeostasis with small molecules as a strategy for the development of pan-coronavirus antiviral therapies

Abstract The COVID-19 pandemic has created a global health crisis, with challenges arising from the ongoing evolution of the SARS-CoV-2 virus, the emergence of new strains, and the long-term effects of COVID-19. Aiming to overcome the development of viral resistance, our study here focused on develo...

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Main Authors: Yu-Qian Mao, Shahrzad Jahanshahi, Ramy Malty, David A. J. Van Ommen, Yimei Wan, Trevor M. Morey, Stephanie H. W. Chuang, Veronika Pavlova, Choudhary Ahmed, Subha Dahal, Funing Lin, Maria Mangos, Jocelyn Nurtanto, Yuetong Song, Terek Been, Natasha Christie-Holmes, Scott D. Gray-Owen, Mohan Babu, Amy P. Wong, Robert A. Batey, Liliana Attisano, Alan Cochrane, Walid A. Houry
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07143-z
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https://doi.org/10.1038/s42003-024-07143-z

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