CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics

This study provides a comprehensive computational analysis of how mechanical heart valve orientations impact left ventricular (LV) hemodynamics, with potential implications for surgical valve placement. Focusing on monoleaflet valves (MLV) and bileaflet valves (BLV), the research explores how differ...

Full description

Saved in:
Bibliographic Details
Main Authors: R.S.V.N. Murty, P. Pabsetti, R. Harish
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Results in Engineering
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590123024018383
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846115722827137024
author R.S.V.N. Murty
P. Pabsetti
R. Harish
author_facet R.S.V.N. Murty
P. Pabsetti
R. Harish
author_sort R.S.V.N. Murty
collection DOAJ
description This study provides a comprehensive computational analysis of how mechanical heart valve orientations impact left ventricular (LV) hemodynamics, with potential implications for surgical valve placement. Focusing on monoleaflet valves (MLV) and bileaflet valves (BLV), the research explores how different valve angles influence blood flow patterns within the LV chamber. The analysis includes velocity contours, streamline patterns, vorticity contours, and temporal velocity fluctuations to elucidate the effects of valve orientation on LV performance. Findings indicate that valve orientation significantly influences flow coherence and blood velocity. For instance, a 20-degree orientation in the MLV alters jet flow in ways that could affect wall shear stress distribution. At a 45-degree angle, the MLV produces a more centralized jet flow, enhancing flow uniformity and aligning more closely with physiological conditions. In contrast, a 55-degree angle skews the jet flow, potentially leading to adverse hemodynamic effects. Similarly, BLV orientations at 45, 55, 60, and 70° showed that lower angles improved flow efficiency, reducing energy losses and minimizing the risk of regurgitation, while higher angles led to turbulent and potentially damaging flow patterns. Comparative results at a 45-degree orientation demonstrated the superior performance of BLV in regulating normal velocity, with BLV reducing average blood velocity by 38.77 % compared to a 29.53 % reduction with MLV. These results underscore the importance of optimizing mechanical heart valve orientations to enhance left ventricular hemodynamics. The findings carry significant clinical implications, supporting evidence-based valve placement decisions that can substantially improve patient outcomes, survival rates and long-term cardiovascular health.
format Article
id doaj-art-34bb9c4693044fb9a1cfbdac1acdea8c
institution Kabale University
issn 2590-1230
language English
publishDate 2024-12-01
publisher Elsevier
record_format Article
series Results in Engineering
spelling doaj-art-34bb9c4693044fb9a1cfbdac1acdea8c2024-12-19T11:00:05ZengElsevierResults in Engineering2590-12302024-12-0124103595CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamicsR.S.V.N. Murty0P. Pabsetti1R. Harish2School of Mechanical Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, 600127, IndiaSchool of Mechanical Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, 600127, IndiaCorresponding author.; School of Mechanical Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, 600127, IndiaThis study provides a comprehensive computational analysis of how mechanical heart valve orientations impact left ventricular (LV) hemodynamics, with potential implications for surgical valve placement. Focusing on monoleaflet valves (MLV) and bileaflet valves (BLV), the research explores how different valve angles influence blood flow patterns within the LV chamber. The analysis includes velocity contours, streamline patterns, vorticity contours, and temporal velocity fluctuations to elucidate the effects of valve orientation on LV performance. Findings indicate that valve orientation significantly influences flow coherence and blood velocity. For instance, a 20-degree orientation in the MLV alters jet flow in ways that could affect wall shear stress distribution. At a 45-degree angle, the MLV produces a more centralized jet flow, enhancing flow uniformity and aligning more closely with physiological conditions. In contrast, a 55-degree angle skews the jet flow, potentially leading to adverse hemodynamic effects. Similarly, BLV orientations at 45, 55, 60, and 70° showed that lower angles improved flow efficiency, reducing energy losses and minimizing the risk of regurgitation, while higher angles led to turbulent and potentially damaging flow patterns. Comparative results at a 45-degree orientation demonstrated the superior performance of BLV in regulating normal velocity, with BLV reducing average blood velocity by 38.77 % compared to a 29.53 % reduction with MLV. These results underscore the importance of optimizing mechanical heart valve orientations to enhance left ventricular hemodynamics. The findings carry significant clinical implications, supporting evidence-based valve placement decisions that can substantially improve patient outcomes, survival rates and long-term cardiovascular health.http://www.sciencedirect.com/science/article/pii/S2590123024018383HemodynamicsMonoleaflet valveBileaflet valveValve orientationsLeft ventricle
spellingShingle R.S.V.N. Murty
P. Pabsetti
R. Harish
CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
Results in Engineering
Hemodynamics
Monoleaflet valve
Bileaflet valve
Valve orientations
Left ventricle
title CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
title_full CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
title_fullStr CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
title_full_unstemmed CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
title_short CFD investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
title_sort cfd investigation of mechanical heart valve orientations in modulating left ventricular hemodynamics
topic Hemodynamics
Monoleaflet valve
Bileaflet valve
Valve orientations
Left ventricle
url http://www.sciencedirect.com/science/article/pii/S2590123024018383
work_keys_str_mv AT rsvnmurty cfdinvestigationofmechanicalheartvalveorientationsinmodulatingleftventricularhemodynamics
AT ppabsetti cfdinvestigationofmechanicalheartvalveorientationsinmodulatingleftventricularhemodynamics
AT rharish cfdinvestigationofmechanicalheartvalveorientationsinmodulatingleftventricularhemodynamics